Title

Impact of nocturnal oxygen supplementation on sleep quality and daytime fatigue among interstitial lung disease (ILD) patients

Authors

Mriganka Madhav Misra*, Deepika Patel, Ashwin Songara & Anindita Bhagawati

Affiliation

Department of Pulmonology, Pulmonologist, Assam Medical College, Dibrugarh, Assam, India; *Corresponding author

Email

Mriganka Madhav Misra - E-mail: drmriganka.misra@gmail.com

Deepika Patel - E-mail: docdeepikapatel@gmail.com

Ashwin Songara - E-mail: ashwin.osr@gmail.com

Anindita Bhagawati - E-mail: bhagawatijimli@gmail.com

Article Type

Research Article

Date

Received April 1, 2026; Revised April 30, 2026; Accepted April 30, 2026, Published April 30, 2026
 

Abstract

A collection of more than 300 conditions known as interstitial lung diseases (ILDs) limit oxygen delivery by generating persistent inflammation and irreversible lung tissue scarring, or fibrosis. There is progressive impairment of gas exchange and are frequently complicate by nocturnal hypoxemia. It remains under-recognized despite its significant impact on sleep quality and daytime functioning. Therefore, it is of interest to report the effect of nocturnal oxygen supplementation on sleep quality and daytime fatigue in patients with interstitial lung disease. Total included 228 participants were randomized into two groups: nocturnal oxygen supplementation (n=114) and placebo (sham oxygen) (n=114). Sleep parameters were assessed using overnight monitoring. The Pittsburgh Sleep Quality Index (PSQI), while daytime fatigue and sleepiness were evaluated using validated scales. Statistical analysis was performed using appropriate inferential tests, with p< 0.05 considered significant. Nocturnal oxygen supplementation significantly improves both objective and subjective sleep parameters while reducing daytime fatigue in ILD patients.

Keywords

Interstitial lung disease (ILD); nocturnal hypoxemia; polysomnography; oxygen therapy; sleep quality; quality of life

Citation

Misra et al. Bioinformation 22(4): 2457-2461 (2026)

Edited by

P Babaji

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.