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Title

Triple phase CT in evaluating indeterminate focal liver lesion

 

Authors

Gaurav Khurana*, Rajesh Kumar, Ashish Kumar Shukla, Parinita Sadhanidar, Sachi Mall & Shipra Chaudhary

 

Affiliation

Department of Radiodiagnosis, Santosh Medical College, Santosh Deemed to Be University, Ghaziabad, Delhi NCR, India; *Corresponding author

 

Email

Gaurav Khurana - E-mail: gauravkhurana082@gmail.com
Rajesh Kumar - E-mail: Drkumar8890@gmail.com

Ashish Kumar Shukla - E-mail: drashish07@rediffmail.com; ashish.shukla@santosh.ac.in
Parinita Sadhanidar - E-mail: pari2311s@gmail.com
Sachi Mall - E-mail: sachi.mall27@gmail.com
Shipra Chaudhary - E-mail: shiprachaudhary7@gmail.com

 

Article Type

Research Article

 

Date

Received April 1, 2026; Revised April 30 2026; Accepted April 30, 2026, Published April 30, 2026

 

Abstract

Indeterminate focal liver lesions (FLLs) detected through ultrasonography or single-phase imaging present a diagnostic challenge due to their varied management depending on whether they are benign or malignant. Therefore, it is of interest to evaluate the diagnostic performance of triple-phase multidetector computed tomography (MDCT) in characterizing these lesions by assessing dynamic contrast enhancement across arterial, portal venous and delayed phases. Results showed that triple-phase CT accurately differentiated benign from malignant lesions, with vascular and enhancement patterns providing key diagnostic insights. Malignant lesions exhibited distinct features, including portal venous hypoenhancement and late-phase washout. Thus, we show the high accuracy of triple-phase CT for managing indeterminate FLLs, supporting better clinical decision-making.

 

Keywords

Benign lesions, diagnosis, focal liver lesions (FLLs), multidetector computed tomography (MDCT), triple-phase CT

 

Citation

Khurana et al. Bioinformation 22(4): 2617-2623 (2026)

 

Edited by

Ritik Kashwani

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.