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Title

Platelet-rich plasma (PRP) versus steroid as an intradiscal injection for lower back aches among degenerative disc disorder patient in India

 

Authors

Jaideep Singh, Urmila Keshari, V. Vignesh Rajan*, Sivasamy Sivakumar & Varsha Manal

 

Affiliation

Department of Anaesthesiology, Gandhi Medical College, Bhopal, Madhya Pradesh, India; *Corresponding author

 

Email

Jaideep Singh - E-mail: singhdrjaideep@gmail.com; Phone: +91 9827767022

Urmila Keshari - E-mail: drsurmi@rediffmail.com; Phone: +91 9826757745

V. Vignesh Rajan - E-mail: drvigrajan1163@gmail.com; Phone: +91 9659395301

Sivasamy Sivakumar - E-mail: ssivasamy96@gmail.com; Phone: +91 94443040812

Varsha Manal - E-mail: varshamanal96@gmail.com; Phone: +91 9496374366

 

Article Type

Research Article

 

Date

Received April 1, 2026; Revised April 30, 2026; Accepted April 30, 2026, Published April 30, 2026

 

Abstract

Degenerative disc disease (DDD) is a major cause of chronic low back pain and optimal minimally invasive treatment remains uncertain. Therefore, it is of interest to compare the efficacy of intradiscal platelet-rich plasma (PRP) versus steroid injections using Visual Analog Scale (VAS) scores. In this prospective study of 60 patients, participants were randomized to receive either triamcinolone or PRP injections weekly for three weeks, with follow-up at two and six months. Steroid injections provided greater short-term pain relief at two months, whereas PRP showed significantly superior pain reduction at six months with lower final VAS scores. Both modalities are effective in the short term, but PRP offers better sustained pain relief and may be preferred for long-term management of degenerative disc disease.

 

Keywords

Platelet rich plasma (PRP), chronic radicular pain, degenerative disc disorder (DDD), visual analog scale (VAS), regenerative therapy

 

Citation

Singh et al. Bioinformation 22(4): 2630-2633 (2026)

 

Edited by

 Neelam Goyal & Shruti Dabi

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.