Title
Concentration-dependent antimicrobial effects of two mouthwashes on key periodontal pathogens: An in vitro study
Authors
M.M Dayakar, Aishwarya Bruhanmath*, Prakash Pai Gurpur, Shivananda K Hiranya, L.S Shilpa, Vidyalakshmi S Rao & Sarja Ishwarya
Affiliation
Department of Periodontology, KVG Dental College and Hospital, Sullia, Karnataka, India; *Corresponding author
M.M Dayakar - E-mail: mmdayakar@yahoo.com; Phone: +919448167427
Aishwarya Bruhanmath - E-mail: bruhanmathaishwarya@gmail.com; kvgdch@gmail.com;
Phone: +919353852262
Prakash Pai Gurpur - E-mail: prakashpaipai2014@gmail.com; Phone:
+919845156405
Shivananda K Hiranya - E-mail: shivanandperio@gmail.com; Phone:
+919900794769
L.S Shilpa - E-mail: shilpasudhakar11@gmail.com; Phone:
+917306123390
Vidyalakshmi S. Rao - E-mail: vidyalakshmi.s.rao15@gmail.com; Phone:
+919900312511
Sarja Ishwarya - E-mail: bruhanmathaishwarya@gmail.com; Phone:
+919591521693
Article Type
Research Article
Date
Received May 1, 2026; Revised May 31, 2026; Accepted May 31, 2026, Published May 31, 2026
Abstract
Periodontal diseases, caused by pathogenic dental plaque biofilm, are often treated with chlorhexidine, but its long-term use can lead to undesirable side effects. Therefore, it is of interest to compare the antimicrobial efficacy of two herbal mouthwashes, Oralife and Ora-T, against periodontal pathogens Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans using the disc diffusion method. Results showed that Oralife exhibited significantly larger zones of inhibition than Ora-T at all tested concentrations. No inhibitory effect was observed at the lowest concentration. Thus, we show Oralife's potential as a more effective herbal alternative for periodontal therapy.
Keywords
Periodontal pathogens, Herbal mouthwash, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Antimicrobial efficacy
Citation
Dayakar et al. Bioinformation 22(5): 2823-2827 (2026)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
