Title

Effect of non-surgical periodontal therapy on salivary pH, flow rate, salivary protein and calcium concentration in patients with chronic generalized periodontitis

Authors

Anuja N Moharir^1,*, Anuja Hakkepatil², Vaishali Pagare³, Prakash Gaikwad⁴, Sabina Shaikh² & Hiroj Bagde⁵

Affiliation

¹Department of Periodontology, D.Y. Patil Dental School, Lohegaon, Pune, Maharashtra, India; ²Department of Conservative Dentistry, Endodontics and Aesthetic dentistry, DY Patil Dental School, Lohegaon, Pune, Maharashtra, India; ³Department of Oral and Maxillofacial Surgery, DY Patil Dental School, Lohegaon, Pune, Maharashtra, India; ⁴Department of Oral Pathology, Sinhagad Dental College and Hospital, Pune, Maharashtra, India; ⁵Department of Periodontology, Government Dental College and Hospital, Chhatrapati Sambhajinagar, Maharashtra, India; *Corresponding author

Email

Anuja N Moharir - E-mail: anujamoharir1@gmail.com
Anuja Hakkepatil - E-mail: anuja.hakkepatil@dypds.com
Vaishali Pagare - E-mail: dr.vaishali.kk@gmail.com
Prakash Gaikwad - E-mail: drprakashgaikwad88@gmail.com
Sabina Shaikh - E-mail: drsabinafshaikh@gmail.com
Hiroj Bagde - E-mail: hirojbagde8@gmail.com

Article Type

Research Article

Date

Received May 1, 2026; Revised May 31, 2026; Accepted May 31, 2026, Published May 31, 2026

Abstract

Periodontitis is an inflammatory disease of the supporting tissues of the tooth. The host-microbial interaction in periodontitis leads to ulceration of sulcular epithelium which acts as a portal of entry for the bacteria to enter the connective tissue and thus into the systemic circulation. Elimination of causative agent through non-surgical periodontal therapy causes a reduction in inflammation and periodontal microbes. Therefore, it is of interest to examine the effect of scaling on salivary flow rate, pH, salivary protein and calcium concentration. A total 50 patients were selected and they were assessed at their first visit and on 2nd day after non-surgical therapy. Unstimulated whole saliva was collected from patients at their first visit and flow rate was noted during collection of the sample. Salivary protein and calcium concentration, pH were estimated before and two days after non-surgical therapy. A positive correlation between the level of calcium and protein level reduction after therapy was seen.

Keywords

Saliva, salivary pH, salivary flow rate, non-surgical therapy

Citation

Moharir et al. Bioinformation 22(5): 2885-2889 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.