Title

Antibacterial efficacy of nano-silver, nano-chitosan and silver diamine fluoride against Streptococcus mutans

Authors

Md Imran^1,*, Shivam Sulok², Karuna Bharti³, Kalpana Thakur⁴, Rudra Mazumdar⁵ & Abhishek Sinha¹

Affiliation

¹Department of Dentistry, Patna Medical College & Hospital, Patna, Bihar, India; ²Department of Prosthodontics and crown & bridge, BJSDCH, Ludhiana, Punjab, India; ³Department of Conservative Dentistry & Endodontics, MMDCH, Darbhanga, India; ⁴Department of Paediatric Dentistry & Preventive Dentistry, MMDCH, Darbhanga, India; ⁵Department Conservative Dentistry & Endodontics, HIDSAR, Haldia, India; *Corresponding author

Email

Md Imran - E-mail: Drimran100009@gmail.com
Shivam Sulok - E-mail: shivamsulok@gmail.com
Karuna Bharti - E-mail: karunabharti198@gmail.com
Kalpana Thakur - E-mail: drsubhansh@gmail.com
Rudra Mazumdar - E-mail: rud183dent@gmail.com
Abhishek Sinha - E-mail: drsinhaabhi@gmail.com

Article Type

Research Article

Date

Received May 1, 2026; Revised May 31, 2026; Accepted May 31, 2026, Published May 31, 2026
 

Abstract

Dental caries in primary teeth remains a major pediatric health concern driven by Streptococcus mutans, necessitating effective antimicrobial strategies. Therefore, it is of interest to compare the antibacterial efficacy of nano silver, nano-chitosan and silver diamine fluoride against S. mutans isolated from carious primary teeth. Hence, an in vitro design using agar well diffusion, minimum inhibitory concentration and minimum bactericidal concentration assays was conducted on samples from 30 extracted primary molars. Nano silver demonstrated the highest antibacterial activity followed by silver diamine fluoride and nano-chitosan, with the lowest MIC observed for nano silver. Thus, we show that nano silver exhibits superior antibacterial potential and may serve as an effective adjunct in pediatric caries management.

Keywords

Nano silver, nano-chitosan, silver diamine fluoride, Streptococcus mutans, primary teeth, antibacterial

Citation

Imran et al. Bioinformation 22(5): 3043-3049 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.