Title
Completion total pancreatectomy (CTP) for isolated PDAC recurrence
Authors
Praveen Singh Baghel, Shailendra Singh Nargesh, Yogesh Savaner*, Shivam Singh Tomar, K M Pinky & Prashant Chauhan
Affiliation
Departments of General Surgery, Dr Laxmi Narayan Pandey Medical College, Ratlam, Madhya Pradesh, India; *Corresponding author
Praveen Singh Baghel - E-mail: prvn.baghel@gmail.com; Phone: +91
9893211181
Shailendra Singh Nargesh - E-mail: shailendranargesh19@gmail.com;
Phone: +91 8878866323
Shivam Singh Tomar - E-mail: shivamtomar618@gmail.com; Phone: +91
8982762343
Yogesh Savaner - E-mail: drspecial26@gmail.com; Phone: +91
7389090568
K M Pinky - E-mail: pinkesh1199@gmail.com; Phone: +91 7895917351
Prashant Chauhan - E-mail: prashantchouhan39@gmail.com; Phone: +91
8718962695
Article Type
Research Article
Date
Received May 1, 2026; Revised May 31, 2026; Accepted May 31, 2026, Published May 31, 2026
Abstract
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a poor prognosis and currently represents the fourth leading cause of cancer-related death. Outcomes of completion total pancreatectomy (CTP) for recurrent pancreatic ductal adenocarcinoma (PDAC) remain insufficiently defined. Therefore, it is of interest to evaluate perioperative safety and oncological outcomes in 84 patients undergoing CTP for isolated PDAC recurrence. Clinical variables including (R0) resection rate, operative parameters, morbidity, mortality and survival outcomes were analyzed. CTP achieved R0 resection in most cases with acceptable morbidity and mortality, while improved survival was associated with disease-free interval >24 months, CA 19-9 <37 U/mL and absence of lymph node metastasis. Thus, we show CTP as a viable salvage option providing meaningful long-term survival in selected patients with recurrent PDAC.
Keywords
Completion total pancreatectomy (CTP), pancreatic ductal adenocarcinoma (PDAC), isolated recurrence, disease-free interval, overall survival, salvage surgery
Citation
Baghel et al. Bioinformation 22(5): 3165-3168 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
