Title

Effect of guided tissue regeneration using bioresorbable membranes on periodontal regeneration in grade II furcation defects

Authors

Rajesh Lohiya^1,*, Kiran Dodani², Ankur singh Rajpoot², Pallavi Goswami¹, Anup Shelke³ & Shilpa Jaiswal¹

Affiliation

¹Department of Periodontology and Implant Dentistry, RKDF Dental College and Research Centre, Bhopal, Madhya Pradesh, India; ²Department of Periodontology, RKDF Dental College and Research Centre, Bhopal, Madhya Pradesh, India; ³Department of Periodontology, Dr HSRSM Dental College and Hospital, Hingoli, Maharashtra, India; *Corresponding author

Email

Rajesh Lohiya - E-mail: ramamarketing1@gmail.com; Phone: +91 8600610201
Kiran Dodani - E-mail: drkasturba79@yahoo.co.in; Phone: +91 7737732117
Ankur singh Rajpoot - E-mail: dr.ankur87@yahoo.com; Phone: +91 9977555400
Pallavi Goswami - E-mail: drpallavigoswami47@gmail.com; Phone: +91 9012280778
Anup Shelke - E-mail: dranup001@gmail.com; Phone: +91 9890395919
Shilpa Jaiswal - E-mail: drshilpa1110@gmail.com; Phone: +91 8840142156

Article Type

Research Article

Date

Received May 1, 2026; Revised May 31, 2026; Accepted May 31, 2026, Published May 31, 2026

Abstract

Grade II furcation defects pose a significant therapeutic challenge in periodontology due to their complex anatomy and limited accessibility for effective regeneration. Therefore, it is of interest to evaluate the efficacy of guided tissue regeneration (GTR) using a bioresorbable collagen membrane compared to open flap debridement (OFD) alone in 48 patients with mandibular molar Grade II furcation defects. Clinical parameters (probing depth, clinical attachment level, horizontal probing depth and gingival recession) and radiographic bone fill were assessed at baseline and 6 months postoperatively. The GTR group demonstrated significantly greater improvements in PD reduction (3.42 ± 0.78 mm vs 2.18 ± 0.65 mm), CAL gain (2.89 ± 0.72 mm vs 1.54 ± 0.58 mm), HPD reduction (2.67 ± 0.54 mm vs 1.23 ± 0.48 mm) and bone fill (48.6 ± 12.3% vs 22.4 ± 9.8%) compared to OFD (p<0.001). GTR with a bioresorbable collagen membrane provides superior clinical and radiographic outcomes, supporting its use as an effective regenerative approach for Grade II furcation defects.

Keywords

Guided tissue regeneration (GTR); bioresorbable membrane; furcation defects; periodontal regeneration; collagen membrane

Citation

Lohiya et al. Bioinformation 22(5): 3186-3191 (2026)

Edited by

Hiroj Bagde

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.