Title
Comparing the efficacy of A-PRF and I-PRF in mandibular 3rd molar surgery with similar difficulty index: A comparative, split mouth study
Authors
Prashanth Subhash Pawar*, Samir Joshi, Sudhir Pawar & Richa Sharma
Affiliation
Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Dhankawadi, Pune, Maharashtra, India; *Corresponding author
Prashanth Pawar - E-mail: Prashantpawar7788@gmail.com
Samir Joshi - E-mail: samirjoshi1671@gmail.com
Sudhir Pawar - E-mail: samirjoshi1671@gmail.com; sudhirpawar6600@gmail.com
Richa Sharma - E-mail: risha120193@gmail.com
Article Type
Research Article
Date
Received June 1, 2026; Revised June 30, 2026; Accepted June 30, 2026, Published June 30, 2026
Abstract
In regenerative dentistry, platelet rich fibrin (PRF) has been used as a concentrated autologous growth factors capable of encouraging tissue regeneration. Hence, ten patients requiring bilateral mandibular third molar extraction with similar difficulty index were included in the study. Following surgical extraction, A-PRF and I-PRF prepared using low-speed centrifugation protocols were placed into the extraction sockets during separate appointments conducted at a two-week interval. Following surgical extraction, A-PRF and I-PRF prepared using low-speed centrifugation protocols were placed into the extraction sockets during separate appointments conducted at a two-week interval. Thus, A-PRF and I-PRF prepared without anticoagulants using a low-speed centrifugation protocol in mandibular third molar surgery.
Keywords
Platelet rich plasma, injectable platelet rich Fibrin (I-PRF), advanced-platelet rich fibrin (A-PRF), third molar surgery, similar difficulty index
Citation
Pawar et al. Bioinformation 22(6): 3219-3225 (2026)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
