Title
Epidemiological and clinicopathological profile of pancytopenia: A cross-sectional study
Authors
N. Chethan1, Divyansh Badole1,*, Zeeshan Farooqui1, Manoj Gupta1 & Sachin Parmar2
Affiliation
1Department of General Medicine, MGMMC & MYH Hospital, Indore, Madhya Pradesh, India; 2Department of Community Medicine V.K.S. Govertment Medical College, Neemuch, Madhya Pradesh, India; *Corresponding author
N. Chethan - E-mail: chethann100@gmail.com
Divyansh Badole - E-mail: djruck101@gmail.com
Zeeshan Farooqui - E-mail: zfarooqui089@gmail.com
Manoj Gupta - E-mail: drmanojgupta24@gmail.com
Sachin Parmar - E-mail: dr.sachinparmar@gmail.com
Article Type
Research Article
Date
Received June 1, 2026; Revised June 30, 2026; Accepted June 30, 2026, Published June 30, 2026
Abstract
Broad etiology of pancytopenia also makes it regionally heterogeneous, requiring a multifaceted clinico-haematological assessment. Hence, this cross-sectional study at MGM medical college and Maharaja Yeshwantrao hospital in Indore involved 200 patients whose CBC, peripheral smear, LFT/RFT, vitamin B12/folate levels and bone marrow were measured within a period of 12 months and had to be above 15 years old with pancytopenia (not under chemotherapy/radiotherapy). Severe anaemia (53.5%), moderate leucopenia (34%), severe thrombocytopenia (25.5%) and 31-40 year-olds had the highest (21.5%) were severe cases; pallor (60%) and dyspnoea (32.5%) were most common. Top causes were vitamin B12 deficiency (28.5%), hypersplenism (12%) and dimorphic anaemia (10.5%) and gender-B12 association had a significant value (p=0.028). Thus, the major reversible cause is nutrition deficiencies, especially the vitamin B12 deficiency, which should be screened and supplemented by communities.
Keywords
Pancytopenia; vitamin B12 deficiency; clinico-haematological profile
Citation
Chethan et al. Bioinformation 22(6): 3348-3351 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
