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Title

Anxiety and panic disorder: First-line pharmacotherapy

 

Authors

Shruti Vihang Brahmbhatt, Akil Idrish Sunasara* & Mahavirsingh Rajput

 

Affiliation

Department of Pharmacology, Shrimati Bhikhiben Kanjibhai Shah Medical Institute and Research Centre, Sumandeep Vidyapeeth Deemed to be University, Piparia, Vadodara- 391760, Gujarat, India; *Corresponding author

 

Email

Shruti Vihang Brahmbhatt - E-mail: dr.shruti1988@gmail.com

Akil Idrish Sunasara - E-mail: akilsunasara81@gmail.com, Phone: +91 9727834668

Mahavirsingh Rajput - E-mail: drvirranawat@gmail.com

 

Article Type

Research Article

 

Date

Received June 1, 2026; Revised June 30, 2026; Accepted June 30, 2026, Published June 30, 2026

 

Abstract

Anxiety and panic disorders are common psychiatric illnesses, but real-world data on first-line pharmacotherapy outcomes from Indian tertiary care settings remain limited. Therefore, it is of interest to evaluate prescribing patterns, efficacy, safety, and tolerability of first-line pharmacotherapy in 40 newly diagnosed patients with anxiety or panic disorder. Anxiety disorder accounted for 72.5% of cases, and SSRIs alone or combined with benzodiazepines were the most frequently prescribed treatment regimens. Favorable clinical outcomes were observed in 77.5% of patients, while adverse drug reactions were predominantly mild and did not require treatment discontinuation. Thus, SSRI-based first-line pharmacotherapy demonstrated good efficacy and tolerability, supporting guideline-based management of anxiety and panic disorders.

 

Keywords

Anxiety disorder; panic disorder (PD); first-line pharmacotherapy; selective serotonin reuptake inhibitors (SSRIs); benzodiazepines

 

Citation

Brahmbhatt et al. Bioinformation 22(6): 3425-3429 (2026)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.