Title
Pulpal response following SDF application for deep carious lesions: An in vivo study
Authors
Shelly Singh1, Sugandha Sharma2,*, Shraddha Shetti3, Ashtha Arya4, Gaurav Mishra5 & Sudha Patil6
Affiliation
1Department of Dentistry , School of dental medicine , Anschutz Medical campus , University of Colorado,Aurora, Colorado, USA; 2Department of Pedodontics, Lather Dental Clinic and Implant Centre, Bhiwani, India; 3Department of Orthodontics, Bharati Vidyapeeth (Deemed to be University, Pune) Dental College and Hospital, Sangli, Maharashtra, India; 4Department of Conservative Dentistry and Endodontics, SGT Dental College, Hospital and Research Institute, SGT University, Gurugram, Haryana, India; 5Department of Pedodontics, College Modern Dental College and Research center Place, Indore, India; 6Department of Pedodontics, ACPM Dental college and Hospital, Sakri Road, Dhule, Maharashtra, India; *Corresponding author
Shelly Singh - E-mail: drshellys76@gmail.com; shelly.singh@cuanschutz.edu
Sugandha Sharma - E-mail: sugandhasharma333@gmail.com
Shraddha Shetti - E-mail: shraddhashetti@gmail.com
Ashtha Arya - E-mail: drashthaarya@yahoo.co.in
Gaurav Mishra - E-mail: gaurav6646@gmail.com
Sudha Patil - E-mail: dr.sudhapatil@gmail.com
Article Type
Research Article
Date
Received June 1, 2026; Revised June 30, 2026; Accepted June 30, 2026, Published June 30, 2026
Abstract
Deep carious lesions often threaten pulpal vitality and limited evidence exists regarding the pulpal response to 38% silver diamine fluoride (SDF) in primary and permanent molars. Therefore, it is of interest to evaluate the pulpal response to 38% SDF in deep carious lesions of primary and permanent molars. Hence, a total of 70 molars (35 primary, 35 permanent) were treated with SDF following selective caries removal and monitored clinically and radiographically for 12 months. Most teeth maintained pulpal vitality, with overall success rates of 80% in primary molars and 85.7% in permanent molars. Failures were mainly associated with spontaneous pain or radiographic periapical changes during follow-up. Thus, we show that SDF is a minimally invasive and biologically compatible option for managing deep caries while preserving pulp vitality in both dentitions
Keywords
Silver diamine fluoride (SDF); deep carious lesions; pulpal response; primary molars; permanent molars; vital pulp therapy; minimally invasive dentistry
Citation
Singh et al. Bioinformation 22(6): 3491-3495 (2026)
Edited by
Rashmi Laddha
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
