Title
Correlation of serum ferritin, D dimer and CRP levels with disease severity among hospitalized patients in India
Authors
Madhur Gupta1, Girish Dubey2, Ritesh Yadav2 & Ramesh Prasad Agrawal3,*
Affiliation
1Department of Biochemistry, N.K.P. Salve Institute of Medical Sciences & Research Centre and Lata Mangeshkar Hospital, Nagpur, Maharashtra, India; 2Department of General Medicine, SRVS Medical College Shivpuri, Madhya Pradesh, India; 3Department of Microbiology, Government Medical College, Satna, Madhya Pradesh, India; *Corresponding author
Madhur Gupta - E-mail: madhurgupta1972@gmail.com; Phone: +91 9422782291
Girish Dubey - E-mail: drgirishdubey@gmail.com; Phone: +91 8745023490
Ritesh Yadav - E-mail: dr.ritesh_123@yahoo.co.in; Phone: +91 9977423070
Ramesh Prasad Agrawal - E-mail: drrameshagrawal22@gmail.com; Phone: +91 7568775748
Article Type
Research Article
Date
Received June 1, 2026; Revised June 30, 2026; Accepted June 30, 2026, Published June 30, 2026
Abstract
Delayed recognition of severe disease in hospitalized patients remains a major challenge and contributes to increased morbidity and mortality. Therefore, it is of interest to evaluate the correlation of serum ferritin, C-reactive protein (CRP) and D-dimer levels with disease severity in hospitalized patients. Hence, a hospital-based cross-sectional study was conducted on 100 adult patients and biomarker levels were measured using standard laboratory methods. The results showed a significant increase in serum ferritin, CRP and D-dimer levels with increasing disease severity (p < 0.001). A strong positive correlation was observed between these biomarkers and disease severity, with D-dimer showing the highest correlation and elevated levels were significantly associated with ICU admission and mortality. Thus, combined assessment of ferritin, CRP and D-dimer is a simple and reliable approach for early risk stratification and prognostication in hospitalized patients.
Keywords
Serum ferritin; C-reactive protein (CRP); D-dimer; disease severity; inflammatory biomarkers; hospitalized patients
Citation
Gupta et al. Bioinformation 22(6): 3572-3575 (2026)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
