Title

Impact of NSAIDs on post-operative bleeding in minor dental and oral surgery: A clinical study

Authors

Harshawardhan Ravindra Kadam¹, Akshit Vermani², Vivek Vivek³, Aishwarya Mahajan⁴, K.Y. Giri⁵, Vaishnavi Thota⁶ & Rahul Tiwari⁷,*

Affiliation

¹Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Sangli 416414, Maharashtra, India; ²Department of Oral and Maxillofacial Surgery, Shaheed Kartar Singh Sarabha Dental College and Hospital, VPO Sarabha, Ludhiana, Punjab, India; ³Department of Dental Surgery, VMMC and Safdarjung Hospital, New Delhi, India; ⁴Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Bareilly, Uttar Pradesh, India; ⁵Department of Oral and Maxillofacial Surgery, Drs. Sudha and Nageswara Rao Siddhartha Institute of Dental Sciences, Chinnaoutpalli, Gannavaram Mandal, Krishna District andhra Pradesh, India; ⁶Dental Hygiene Student (Masters in Biomedical Science – Dental Scholar Track and Masters in Healthcare Administration), United States; ⁷Department of Dental Research Cell, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune 411018, Maharashtra, India; *Corresponding author

Email

Harshawardhan Ravindra Kadam - E-mail: harshwardhankadam@gmail.com

Akshit Vermani - E-mail: akshitvermani@gmail.com

Vivek Vivek - E-mail: drvivekswami@gmail.com

Aishwarya Mahajan - E-mail: amahajan2895@gmail.com

K.Y. Giri - E-mail: dr.kolligiriomfs@gmail.com

Vaishnavi Thota - E-mail: vaishut@outlook.com

Rahul Tiwari - E-mail: rahul.tiwari@dpu.edu.in

Article Type

Research Article

Date

Received June 1, 2026; Revised June 30, 2026; Accepted June 30, 2026, Published June 30, 2026

Abstract

Post-operative bleeding is a common concern after minor dental and oral surgical procedures. NSAID use after surgery remains controversial because of its potential effect on platelet aggregation and bleeding time. A prospective observational study was conducted on 100 patients undergoing routine dental extractions, third molar surgery, alveoloplasty, or minor soft tissue procedures. All patients received NSAID-based analgesic regimens following surgery. Statistical analysis demonstrated no significant association between NSAID administration and clinically significant post-operative bleeding. Thus, we show that NSAIDs can be safely prescribed following minor oral surgical procedures when appropriate surgical technique and local hemostatic measures are employed.

Keywords

Non-steroidal anti-inflammatory drugs (NSAIDs); post-operative bleeding; oral surgery; dental extraction; analgesics

Citation

Kadam et al. Bioinformation 22(6): 3604-3608 (2026)

Edited by

Vini Mehta  

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.