Title

Serum bilirubin level in predicting the severity of acute appendicitis

Authors

Prasheelkumar Premnarayan Gupta¹, Vrashabhan Ahirwar², Kaushlendra Singh Narwariya³,*, Talha Saad⁴, Prakash Bhuriya⁵, Satyendra Mishra⁶ & Satyendra Uike⁷

Affiliation

¹Department of Neurosurgery, LN Medical College & JK Hospital, Bhopal, Madhya Pradesh, India; ²Department of Radiology, Bundelkhand Government Medical College, Sagar, Madhya Pradesh, India; ³Department of Surgery, SRVS Medical College, Shivpuri, Madhya Pradesh, India; ⁴Department of Respiratory Medicine, Bundelkhand Medical College Sagar ,Madhya Pradesh, India; ⁵Department of Surgery, Bundelkhand Medical College, Sagar, Madhya Pradesh, India; ⁶Department of Respiratory Medicine, Bundelkhand Medical College Sagar, Madhya Pradesh, India; ⁷Department of Emergency Medicine, Bundelkhand Government Medical College, Sagar, Madhya Pradesh, India; *Corresponding author

Email

Prasheelkumar Premnarayan Gupta - E-mail: prasheelgupta@gmail.com

Vrashabhan Ahirwar - E-mail: drvrashabhan@gmail.com

Kaushlendra Singh Narwariya - E-mail: dr.k.s.narwariya@gmail.com

Talha Saad - E-mail: dr.talhasaad@gmail.com

Prakash Bhuriya - E-mail: prakashbhuriya45@gmail.com

Satyendra Mishra - E-mail: satyendrasgo@gmail.com

Satyendra Uike - E-mail: last21dream@yahoo.com

Article Type

Research Article

Date

Received June 1, 2026; Revised June 30, 2026; Accepted June 30, 2026, Published June 30, 2026

Abstract

Late diagnosis of acute appendicitis escalates the plausibility of appendicular perforation emerging in inflammation of peritoneum. Therefore, it is of interest to determine the levels of serum bilirubin help in prediction of acute inflammation of appendix. A moderately positive association was seen among the levels of serum bilirubin and seriousness of disease with spearman analysis (ρ = 0.41, p < 0.001). Augmented values of bilirubin exhibit a powerful link with appendix inflammation and a prognostic marker for governing complicated cases like perforation. Thus, data shows the bilirubin values as everyday diagnostic workup may assist in the premature identification of appendix inflammation boosting the clinical outcomes.

Keywords

Serum bilirubin, appendicitis, appendicular perforation, hyperbilirubinemia

Citation

Gupta et al. Bioinformation 22(6): 3773-3776 (2026)

Edited by

Vini Mehta  

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.