Title
Efficacy and safety of shigru (Moringa oleifera) leaf powder in metabolic syndrome: A randomized controlled trial protocol
Authors
Danish Javed1,*, Mahadev Meena2, Ashok Kumar3, Ranjana Pandey1 & Sana Anwar2
Affiliation
1Department of AYUSH, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India; 2Department of General medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India; 3Department of Biochemistry, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India; 4Department of Community and Family medicine, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India; *Corresponding author
Danish Javed - E-mail: danish.ayush@aiimsbhopal.edu.in
MahadevMeena - E-mail: mahadev.genmed@aiimsbhopal.edu.in
Ashok Kumar - E-mail: ashok.biochemistry@aiimsbhopal.edu.in
RanjanaPandey - E-mail: ranjana.ayush@aiimsbhopal.edu.in
Sana Anwar - E-mail: sana.phd2022@ aiimsbhopal.edu.in
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Metabolic syndrome is characterized by insulin resistance, obesity, dyslipidemia and hypertension and many patients do not achieve adequate glycemic control despite standard therapy. Therefore, it is of interest to compare the effects of Moringa oleifera leaf powder (MOLP) plus standard of care (SOC) versus SOC alone in 110 adults with metabolic syndrome over 12 weeks. The intervention group will receive MOLP 12 g/day along with metformin and glimepiride, while the control group will receive SOC alone. Thus, data shows the HbA1c as well as other glycemic parameters, insulin resistance, anthropometry, blood pressure, lipid profile, inflammatory markers, organ function and safety of MOLP in metabolic syndrome cases.
Keywords
Metabolic syndrome; hypertension; diabetes mellitus, type 2; dyslipidemias; obesity; cardiometabolic risk factors
Citation
Javed et al. Bioinformation 22(7): 3808-3816 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
