Title
Association of metabolic syndrome with benign prostatic hyperplasia: A cross-sectional study
Authors
Mohammad Toseef¹, Krishna Kumar², Durgesh Kumar Sharma³,*, Manish Swarnkar² & Narendra Kumar Dadsena²
Affiliation
¹Department of General Surgery, LN Medical College, Bhopal, Madhya Pradesh, India; ²Department of General Surgery, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India; ³Department of Community Medicine, Gandhi Medical College, Bhopal, Madhya Pradesh, India;*Corresponding Author
Mohammad Toseef – E-mail: captancool4321@gmail.com; Phone +91-62631715899
Krishna Kumar – E-mail: krishna.tem@aiimsbhopal.edu.in; Phone: +91-9479824972
Durgesh Kumar Sharma – E-mail: durgesh.sharma1512@gmail.com; Phone: +91-9826956701
Manish Swarnkar – E-mail: manish.surgery@aiimsbhopal.edu.in; Phone: +91-9763703920
Narendra Kumar Dadsena – E-mail: narendra.dadsena@gmail.com; Phone: +91-9343268360
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Benign prostatic hyperplasia (BPH) is one of the most common urological conditions affecting aging males and is frequently associated with lower urinary tract symptoms that significantly impair quality of life. In recent years, increasing evidence has suggested a possible relationship between metabolic syndrome and the development and progression of BPH; however, the exact nature of this association remains unclear and requires further evaluation. This observational study of 112 BPH patients at a tertiary care center assessed the relationship between metabolic syndrome and prostate size, symptom severity and treatment outcomes over 18 months. Metabolic syndrome was present in 44.6% of patients and was associated with greater age, higher annual prostate growth rate, elevated HbA1c and severe AUA symptom scores. Thus, data shows the metabolic factors may contribute to BPH progression and that early detection and control of metabolic syndrome could help slow disease advancement.
Keywords
Benign prostatic hyperplasia (BPH), metabolic syndrome (MetS), prostate growth, AUA score, HbA1c, observational study
Citation
Toseef et al. Bioinformation 22(7): 3907-3911 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
