Title
Lifestyle modification and dietary intervention for gestational diabetes mellitus prevention
Authors
Bishan Singh1,*, Sara Siddiqui2, Sangeeta Gupta3, Subhashree Sethi4, Pierina Inés Cantos Márquez5 & Gina Gabriela Aldaz Cadena6
Affiliation
1Department of Physiology, Santosh Medical College and Hospital, Santosh Deemed to be University, Ghaziabad, Uttar Pradesh, India; 2Department of Physiology, Integral Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; 3Department of Physiology, AIIMS Gorakhpur, Uttar Pradesh, India; 4Department of Gynaecologic Oncology, Obstetrics and Gynaecology, AIIMS Bhubaneswar, Odisha, India; 5Department of Medicine, University of Guayaquil, Quito, Ecuador; 6Department of Mental Health, Armed Forces Specialty Hospital No. 1, Quito, Ecuador; *Corresponding author
Bishan Singh - E-mail: drbishan1989@gmail.com
Sara Siddiqui - E-mail: sarasiddiqui@iul.ac.in
Sangeeta Gupta - E-mail: drsangeeta77.65@rediffmail.com
Subhashree Sethi - E-mail: subhashree13sethi@gmail.com
Pierina Inés Cantos Márquez - E-mail: pierina094@gmail.com
Gina Gabriela Aldaz Cadena - E-mail: gina.aldazcaden@outlook.com
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Gestational diabetes mellitus (GDM) affects up to 14% of pregnancies and increases maternal and neonatal complications. Therefore, it is of interest to evaluate the structured lifestyle modification and dietary intervention among 120 high-risk pregnant women randomized into intervention and control groups. The intervention group showed a significantly lower GDM incidence than controls (13.3% vs. 28.3%; p=0.04). Significant improvements were observed in fasting and postprandial glucose, HbA1c, insulin resistance and gestational weight gain. Thus, data shows the intervention also reduced macrosomia, improved neonatal APGAR scores and supported better postpartum glycemic outcomes, supporting its integration into routine antenatal care.
Keywords
Gestational diabetes mellitus (GDM), dietary intervention, lifestyle modification, physical activity, glycaemic control, low-glycaemic index, antenatal care, randomised controlled trial
Citation
Singh et al. Bioinformation 22(7): 4018-4022 (2026)
Edited by
Ruby Singh
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
