Title
Zinc oxide nanoparticles for dental applications: A narrative review
Authors
S. Sindhuja Devi 1, 2, B. Sathyapriya Lakshmanan3,*, Effie Edsor4, G. Balaji2,* & Revathi Duraisamy5
Affiliation
1Department of Oral and Maxillofacial Surgery, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India; 2Department of Oral and Maxillofacial Surgery, Rajas Dental College and Hospital, Kavalkinaru, Tirunelveli, Tamil Nadu, India; 3Department of Anatomy, Balaji Dental College and Hospital, Selaiyur, Chennai, Tamil Nadu, India; 4Department of Oral and Maxillofacial Surgery, RVS Dental College and Hospital, Coimbatore, Tamil Nadu, India; 5Department of Prosthodontics, Saveetha Dental College and Hospital, Chennai, Tamil Nadu, India; *Corresponding author
S. Sindhuja Devi - E-mail: dr.sindhujadevi@rajasdentalcollege.edu.in; Phone: +91 9524170007
Sathyapriya Lakshmanan B - E-mail: sathyapriyas.anatomy@sbdch.bharathuniv.ac.in; Phone: +91 9600033301
Effie Edsor - E-mail: effieedsor@gmail.com; Phone: +91 9488830111
G. Balaji - E-mail: balajigs110@gmail.com; Phone: +91 8248444015
Revathi Duraisamy -E-mail: revathi.sdc@saveetha.com; Phone: +91 7598267022
Article Type
Review
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Oral biofilms and antimicrobial resistance reduce the durability of dental materials. ZnO-NPs offer broad antimicrobial activity and can be incorporated into resins, cements, coatings and drug carriers. Therefore, it is of interest to describe the synthesis, mechanisms, dental applications, biocompatibility and comparison with other nanoparticles. Evidence suggests that optimized ZnO loading reduces biofilm formation without major loss of material performance. Thus, data shows the standardized synthesis, long-term safety testing and clinical trials are required before routine dental use.
Keywords
Zinc oxide nanoparticles (ZnO-NPs), dental biomaterials, antimicrobial activity, biofilms, nanocomposites, biocompatibility
Citation
Devi et al. Bioinformation 22(7): 4028-4033 (2026)
Edited by
Hiroj Bagde
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
