Title

Dyslipidemia and its association with fatty liver severity in non-alcoholic fatty liver disease: Evidence from North India study

Authors

Preeti Singh Dhoat¹, Rohit Raina¹, Navdeep Singh Dhaot², Madhur Verma³, Amandeep Kaur^1,* & Sharanjot Kaur¹

Affiliation

¹Department of General Medicine, All India Institute of Medical Sciences, Bathinda, Punjab, India; ²Department of Paediatric Surgery, All India Institute of Medical Sciences, Bathinda, Punjab, India; ³Department of Community and Family Medicine, All India Institute of Medical Sciences, Bathinda, Punjab, India; *Corresponding author

Email

Preeti Singh Dhoat - E-mail: drpreetidhoat@gmail.com

Rohit Raina - E-mail: rohitraina103@yahoo.com

Navdeep Singh Dhoat - E-mail: drndhoat@gmail.com

Madhur Verma - E-mail: drmadhurverma@gmail.com

Amandeep Kaur-E-mail: dramandeepsandhu@gmail.com

Sharanjot Kaur - E-mail: sharanjot.88@gmail.com

Article Type

Research Article

Date

Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026

Abstract

Non-alcoholic fatty liver disease (NAFLD) is increasingly prevalent and closely associated with metabolic abnormalities, particularly dyslipidemia. Therefore, it is of interest to evaluate the association between dyslipidemia, fatty liver severity (FIB4 score) and liver fibrosis in 112 NAFLD patients attending a tertiary care centre in North India. A significant positive correlation was observed between LDL cholesterol and FIB-4 score; LDL cholesterol and triglycerides also showed a moderate positive correlation with fatty liver grade; LDL/HDL ratio demonstrated a significant association with fatty liver grade and patients with dyslipidemia exhibited higher FIB-4 scores. Thus, data shows that routine lipid assessment and management of dyslipidemia may help identify and treat NAFLD patients at higher risk for advanced liver disease and cardiovascular risks.

Keywords

Non-alcoholic fatty liver disease (NAFLD); dyslipidemia; LDL cholesterol; liver fibrosis; FIB-4 score; fatty liver grade

Citation

Dhoat et al. Bioinformation 22(7): 4086-4092 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.