Title
Homeopathic denture cleansers: A promising natural and biocompatible alternatives to conventional chemical cleanser - An in vitro study
Authors
Hiyangleima Laishram, Varun Kumar* & Jyotsna Seth
Affiliation
Department of Prosthodontics and Crown & Bridge, Seema Dental College and Hospital, Rishikesh, Uttarakhand, India; *Corresponding author
Hiyangleima Laishram - E-mail: hiyangleima1907@gmail.com
Varun Kumar - E-mail: drvarun_smile@yahoo.co.in
Jyotsna Seth - E-mail: drjyotsnaseth64@gmail.com
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Conventional denture cleansers may cause discoloration, surface changes and mucosal irritation with prolonged use. Therefore, it is of interest to evaluate the antifungal efficacy of Azadirachta indica, Cinchona officinalis and Zingiber officinale on acrylic denture specimens over 90 days. Azadirachta indica showed the strongest and most sustained antifungal activity against Candida albicans. Cinchona officinalis showed the lowest long-term efficacy, while Zingiber officinale exhibited moderate activity with gradual decline (p < 0.001). Thus, Azadirachta indica is a sustained-action, biocompatible natural alternative for denture hygiene in edentulous patients.
Keywords
Denture base resins, colony-forming units; denture cleansers, homeopathic medicines, antifungal activity, Candida species, Azadirachta indica, Cinchona officinalis, Zingiber officinale
Citation
Laishram et al. Bioinformation 22(7): 4103-4107 (2026)
Edited by
Ruby Singh
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
