Title

Premature coronary artery disease in young Indian adults

Authors

Kripasindhu Maurya¹, Abinash Agarwala^2,* & Arbind Kumar Choudhary³

Affiliation

¹Department of Cardiology, Jagannath Gupta Institute of Medical Sciences and Hospital (JIMSH), Kolkata, West Bengal, India; ²Department of Chest Medicine (Respiratory Medicine), Midnapore Medical College & Hospital, Midnapore, West Bengal, India; ³Department of Pharmacology, Government Erode Medical College and Hospital, Erode District, Tamil Nadu, India; *Corresponding author

Email

Kripasindhu Maurya - E-mail: kripasindhumaurya@gmail.com

Abinash Agarwala - E-mail: abinash_agarwala@rediffmail.com

Arbind Kumar Choudhary - E-mail: arbindkch@gmail.com

Article Type

Research Article

Date

Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026

Abstract

Premature coronary artery disease (CAD) in young Indian adults has major clinical relevance, but angiographic data from Eastern India remain limited. This cross-sectional observational study included 270 consecutive adults aged 18-40 years who underwent coronary angiography for acute coronary syndrome or objective myocardial ischaemia at a tertiary hospital in Kolkata from April 2020 to September 2021. Obstructive CAD was defined as >=70% stenosis in a major epicardial artery or >=50% stenosis in the left main coronary artery; the mean age was 36.0 +/- 3.55 years, 74.1% were men and obstructive CAD was present in 63.7%. Single vessel disease was the commonest CAD pattern, left anterior descending artery involvement was frequent, smoking was strongly associated with CAD and triglyceride levels were higher in CAD patients. Thus, data shows that early tobacco cessation and targeted assessment of atherogenic dyslipidaemia in young Indian adults.

Keywords

Premature coronary artery disease (CAD), young adults, Eastern India, coronary angiography, single-vessel disease, smoking, dyslipidemias, risk factors

Citation

Maurya et al. Bioinformation 22(7): 4209-4215 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.