Title
Peri-implant dysbiosis: Current perspectives and microbial dynamics
Authors
Vineeta Gupta1, Manisha Kumari1,*, Deepesh Gupta2, Shashank Agrawal1, Harsha Goyal1 & Tanisha Shrivastava1
Affiliation
1Department of Periodontics, Government Dental College, Raipur, Chhattisgarh, India; 2Department of Oral and Maxillofacial Prosthodontics and Implantology, Government Dental College, Raipur, Chhattisgarh, India; *Corresponding author
Vineeta Gupta - E-mail: vinleo76@gmail.com
Manisha Kumari - E-mail: whymanisha@gmail.com
Deepesh Gupta - E-mail: dr_deepesh25@yahoo.co.in
Shashank Agrawal - E-mail: shashanka202@gmail.com
Harsha Goyal - E-mail: harshagoyal075@gmail.com
Tanisha Shrivastava - E-mail: shrivastavatanisha672@gmail.com
Article Type
Review
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Dental implants are a predictable treatment option for tooth replacement, but peri-implant diseases remain a major challenge to their long-term success. Emerging evidence indicates that these diseases result from peri-implant microbial dysbiosis and disruption of host–microbial homeostasis rather than biofilm accumulation alone. Disease progression results in shift to pathogenic communities, including keystone pathogens and implant-adapted opportunistic species that promote leads to peri-implant bone loss. This review summarizes the current evidence on the composition, dynamics and pathogenic mechanisms of the peri-implant microbiota, with emphasis on implant-specific microbial interactions. Thus, data shows that understanding these microbial changes may facilitate early diagnosis and develop targeted preventive and therapeutic strategies for peri-implant diseases.
Keywords
Dental implants, peri-implantitis, microbial dysbiosis, microbial spectrum
Citation
Gupta et al. Bioinformation 22(7): 4234-4239 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
