Title
Intraperitoneal levobupivacaine with dexamethasone and dexamethasone for post-operative pain after laparoscopic cholecystectomy
Authors
Shalini Jain, Rahul Shastre* & Ravi Barde
Affiliation
Department of Anaesthesia, MGM Medical College, Indore, Madhya Pradesh, India; *Corresponding author
Shalini Jain - E-mail: drshalininjain@gmail.com
Rahul Shastre - E-mail: rahulshastrye1997@gmail.com
Ravi Barde - E-mail: barde.ravi@yahoo.com
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Post-operative pain after laparoscopic cholecystectomy remains clinically important and may delay early recovery despite minimally invasive surgery. This prospective observational comparative study included 70 ASA I–II patients undergoing elective laparoscopic cholecystectomy, with 35 patients receiving intraperitoneal levobupivacaine alone and 35 receiving levobupivacaine with dexamethasone. Group LD showed lower VAS score up to 8 hours, longer time to first rescue analgesia than Group LL (414.63 ± 54.48 vs 268.83 ± 75.62 minutes) and lower total rescue analgesic dose (90.00 ± 30.44 vs 115.71 ± 37.91 mg). Thus, data shows that intraperitoneal levobupivacaine with dexamethasone was associated with better early post-operative analgesic profile without clinically significant hyperglycemia or recorded side effects.
Keywords
Laparoscopic cholecystectomy; intraperitoneal analgesia; levobupivacaine; dexamethasone; post-operative pain; rescue analgesia; VAS score.
Citation
Jain et al. Bioinformation 22(7): 4279-4282 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
