Title
Assessment of thyroid status in prediabetes
Authors
G. Hariprasath1, B. Jyothirmayi1, P. Ramana Sai1 & K. Senthil Kumar2,*
Affiliation
1Department of Biochemistry, Madha Medical College & Research Institute, Chennai, Tamil Nadu, India; 2Department of Physiology, Madha Medical College & RI, Tamil Nadu, India; *Corresponding author
G. Hariprasath - E-mail: gopal.hariprasath@gmail.com; Phone: +91 8838736107
B. Jyothirmayi - E-mail: drjyothi71@gmail.com
P. Ramana Sai - E-mail: parasugani71@gmail.com
K. Senthil Kumar - E-mail: drksk.cool@gmail.com; Phone: +91 9940416604
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Prediabetes and thyroid dysfunction are common endocrine disorders that may influence the progression of diabetes and its complications. Therefore, it is of interest to evaluate the thyroid status in 129 prediabetic subjects and 100 healthy controls using fasting plasma glucose, postprandial plasma glucose, glycated hemoglobin and thyroid profile measurements. Glycemic parameters were significantly higher in prediabetic subjects than in controls (p<0.01). Serum thyroid-stimulating hormone levels were significantly higher in prediabetic subjects despite remaining within the normal reference range, whereas free triiodothyronine and free thyroxine levels showed no significant differences between groups. Thus, data shows that early thyroid functional alterations in prediabetes and support regular thyroid screening for timely detection of endocrine abnormalities.
Keywords
Thyroid hormones, screening, prediabetes, thyroid dysfunction and diabetes mellitus
Citation
Hariresath et al. Bioinformation 22(7): 4346-4349 (2026)
Edited by
A Prashanth
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
