Title
Prevalence and impact of silent myocardial ischemia in diabetic patients
Authors
Anurag Rawat1, Tanveen Kaur Soni2, Revanth Madhadi3, Praveenya Pulagam4, Siddhant Mishra5,* & Ram Diwakar6
Affiliation
1Department of Cardiology, Himalayan Institute of Medical Science, Uttarakhand, India; 2Department of Biotechonolgy, JIS University, Kolkata, West Bengal, India; 3Department of General Medicine, Pathima Institute of Medical Sciences, Karimnagar, Telangana, India; 4Department of General Medicine Sri Devraj Urs Medical College, Karnataka, India; 5Department of BCM Kokilaben Dhirubhai Ambani Hospital, Indore, Madhya Pradesh, India; 6Department of General Medicine, Maharshi Vashishtha Autonomous State Medical College Basti, Uttar Pradesh, India; *Corresponding author
Anurag Rawat - E-mail: anuragrwt@gmail.com
Tanveen Kaur Soni - E-mail: tanveenkaur243@gmail.com
Revanth Madhadi - E-mail: revanth.madadi@gmail.com
Praveenya Pulagam - E-mail: praveenya7995@gmail.com
Siddhant Mishra - E-mail: mrsiddhant1994@gmail.com
Ram Diwakar - E-mail: diwakarkgmc08@gmail.com
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Silent myocardial ischemia (SMI) is a frequent, unrecognized complication in patients with type 2 diabetes mellitus (T2DM) that significantly increases adverse cardiovascular risk despite the absence of typical anginal symptoms. Therefore, it is of interest to evaluate the prevalence of SMI and identified its associated clinical risk factors within a diabetic cohort. A total of 240 patients with T2DM were enrolled in this cross-sectional study and baseline demographics, clinical histories and laboratory parameters were systematically analyzed to identify predictors of SMI. Data show that 132 (55.0%) males and 108 (45.0%) females, with statistical analysis revealing that poor glycemic control, longer duration of diabetes, hypertension and dyslipidemia were significant independent predictors of SMI within this population. Thus, SMI is strongly linked to preventable metabolic and clinical markers in T2DM patients, emphasizing the urgent clinical need for targeted screening strategies to enable early detection and aggressive cardiovascular risk reduction.
Keywords
Silent myocardial ischemia (SMI); diabetes mellitus (DM); cardiovascular risk factors; glycemic control; screening
Citation
Rawat et al. Bioinformation 22(7): 4350-4353 (2026)
Edited by
Rashmi Laddha
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
