Title
Clinical evaluation of Nilavagai Chooranam in moolam (Grade I–III internal hemorrhoids): A single-arm pre-post study
Authors
S. Venkatesh*, H. Nalini Sofia & H. Vetha Merlin Kumari
Affiliation
Department of Maruthuvam, National Institute of Siddha, Tambaram Sanatorium, Tamil Nadu, India; *Corresponding author
S. Venkatesh - E-mail: venkatesh.spkv@gmail.com; Phone: +91 9659418223
H. Nalini Sofia - E-mail: h.nalinisofia.nis@gov.in
H. Vetha Merlin Kumari - E-mail: vetha.nis@gov.in
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Moolam (Grade I–III internal hemorrhoids) remains prone to recurrence after conventional treatment, highlighting the need for effective traditional therapies. Therefore, it is of interest to evaluate the Nilavagai Chooranam in 30 patients treated with 1.375 g twice daily for 48 days (CTRI/2024/04/066321). Clinical assessment showed a significant reduction in HSS scores from 8.43 ± 1.55 to 3.13 ± 1.38 (p < 0.001). All moderate and severe cases improved to mild severity and proctoscopy showed reduction in pile mass in all participants. Thus, data show the clinical evidence that Nilavagai Chooranam is associated with significant reductions in Hemorrhoid Symptom Severity (HSS) scores and pile mass in patients with Grade I–III internal hemorrhoids, supporting its potential as a Siddha therapeutic intervention warranting further evaluation in randomized controlled trials.
Keywords
Nilavagai Chooranam, siddha, moolam, internal hemorrhoids, poly herbal formulation
Citation
Venkatesh et al. Bioinformation 22(7): 4464-4471 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
