Title
Significance of positive cardiac troponin in patients with normal ECG: A comparative analysis
Authors
Parnavi Bhagat, Yogita Mukati & Ravi Panwar*
Affiliation
Department of General Medicine, Nandkumar Singh Chouhan Government Medical College, Khandwa, Madhya Pradesh, India;*Corresponding author
Parnavi Bhagat - E-mail: drparnavi7@gmail.com; Phone: +91 8085496164
Yogita Mukati - E-mail: yogitamukati21@gmail.com; Phone: +91 7869046807
Ravi Panwar - E-mail: aarpanwar585@gmail.com; Phone: +91 7566346475
Article Type
Research Article
Date
Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026
Abstract
Elevated cardiac troponin with normal ECG creates diagnostic uncertainty despite troponin's sensitivity for myocardial injury, particularly in early or non-ST elevation infarction. Therefore, it is of interest to compare the 100 patients with suspected cardiac symptoms, categorizing them into troponin-positive/normal ECG versus troponin-negative/abnormal ECG groups for clinical, etiological and outcome analysis. Troponin-positive/normal ECG patients frequently had myocardial infarction or serious cardiac conditions despite absent ECG changes, requiring comprehensive evaluation. Early recognition and aggressive management of these patients significantly improved clinical outcomes and reduced morbidity compared to standard ECG-based protocols. Thus, data shows that troponin-positive/normal ECG as a high-risk phenotype warranting urgent intervention beyond conventional electrocardiographic assessment.
Keywords
Troponin, normal electrocardiography (ECG), acute coronary syndrome (ACS), non-ST elevation myocardial infarction (NSTEMI), cardiac biomarkers, comparative study
Citation
Bhagat et al. Bioinformation 22(7): 4517-4520 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
