Title

Correlation of serum adiponectin with glycemic control and lipid profile in newly diagnosed type 2 diabetes mellitus patients

Authors

N. Soumya¹, B.R Balaji² & D. Selvakumar^3,*

Affiliation

¹Department of Biochemistry, Sri Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar, India; ²Department of Biochemistry, APS Medical College Hospital and Research Institute Mevalurkuppam Village, Valarpuram Post, Sriperumbudur Taluk, Kanchipuram District, Tamil Nadu, India; ³Department of Biochemistry, Dhanalakshmi Srinivasan Institute of Medical Sciences and Hospital, Thuraiyur Road, Perambalur, Tamil Nadu, India; *Corresponding author

Email

N. Soumya - E-mail: drsoumyaravind@gmail.com

B.R Balaji - E-mail: balajibr92@gmail.com

D. Selvakumar - E-mail: selvadbio@gmail.com

Article Type

Research Article

Date

Received July 1, 2026; Revised July 31, 2026; Accepted July 31, 2026, Published July 31, 2026

Abstract

Type 2 diabetes mellitus is a one of the leading disease had highest mortality and morbidity in worldwide, which is due to relative are absolute insulin deficiency and resistance adiponectin is a adipocytokine with primary role of regulating carbohydrate and lipid metabolism through insulin secretion and sensitivity in tissues. Therefore, it is of interest to correlate the serum adiponectin with glycemic control and lipid profile in newly diagnosed type 2 diabetes mellitus patients. This study recruited a total one hundred and twenty subjects, among this sixty type 2 diabetes mellitus and remaining were healthy controls. The fasting venous blood sample were collected for measurement of blood sugars, glycated hemoglobin and lipid profile and adiponectin levels. Serum adiponectin levels were significantly decreased in type 2 diabetes mellitus patients when compared to controls and these levels were inversely correlated with blood sugars, glycated hemoglobin, total cholesterol, triglycerides, very low-density lipoprotein and low-density lipoprotein (P=0.001**). Thus, data show that serum adiponectin might be considered a clinically relevant potential and therapeutic marker for management of blood sugars and lipid profile in newly diagnosed type 2 diabetes mellitus patients.

Keywords

Adiponectin, glycated hemoglobin, glycemic control, lipid profile and type 2 diabetes mellitus (T2DM)

Citation

Soumya et al. Bioinformation 22(7): 4542-4545 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.