Title

Comparative evaluation of cryotherapy and topical anaesthetic on injection pain in endodontic patients

Authors

Amit Kumar¹, Anil Raj², Aishwarya Handa^3,*, Shreya Gill⁴, Neetu Shrivastava⁵, Anisha Luthra⁶ & Pratik Surana⁷

Affiliation

¹Department of Dentistry, Shri Gauri Shankar Medical College & Hospital, Dhanarua, Patna, Bihar; ²Department of Public Health Dentistry, Patna Dental College and Hospital, Patna, Bihar, India; ³Department of Conservative Dentistry & Endodontics, Bharati Vidyapeeth Deemed to be University Dental College and Hospital, Pune, Maharashtra, India; ⁴Department of Conservative Dentistry and Endodontics, Winchester Dental Care, Virginia, USA; ⁵Department of Conservative Dentistry and Endodontics, Bhabha College of Dental Sciences, Bhopal, Madhya Pradesh, India; ⁶Department of Conservative Dentistry and Endodontics, Teerthankar Mahaveer Dental College and Research Centre, TMU Moradabad, Uttar Pradesh, India; ⁷Department of Pedodontics and Preventive Dentistry, Maitri College of Dentistry and Research Centre, Durg, Chhattisgarh, India; *Corresponding author

Email

Amit Kumar - E - mail: endoamit@gmail.com; Phone: +91 8866541984
Anil Raj - E - mail: rajdranil@gmail.com; Phone: + 91 9244263101
Aishwarya Handa -E-mail: aishwarya_h@hotmail.com; Phone: +91 9822318623
Shreya Gill - E-mail: shreyagill101@gmail.com; Phone: +91 92171 14304
Neetu Shrivastava – E-mail: drnkharat@gmail.com; Phone: + 91 9425609795
Anisha Luthra – E-mail - anishaluthra25@gmail.com; Phone + 91 8979661600
Pratik Surana - E-mail: suranadrpratik@gmail.com; Phone: +91 8871310111

Article Type

Research Article

Date

Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026

Abstract

Pain during intraoral local anaesthetic injection remains a significant concern in endodontic patients. Therefore, it is of interest to evaluate the effect of cryotherapy and topical anaesthetic agents on pain perception in 30 adult patients. Participants were randomly allocated into three groups: 2% lignocaine gel, cryotherapy and cryotherapy combined with 2% lignocaine gel. Pain perception was evaluated by the Visual Analogue Scale (VAS). The combination group showed the lowest pain scores, suggesting that cryotherapy adjunct to topical anaesthetic may serve as effective approach for reducing injection pain.

Keywords

Cryotherapy, topical anaesthetic, lignocaine gel, injection pain, endodontics, visual analogue scale (VAS)

Citation

Kumar et al. Bioinformation 22(8): 4712-4716 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.