Title
Physicochemical evaluation of novel nano-calcium hydroxide-based intracanal medicaments: An in vitro study
Authors
G. Sanjana Reddy, Vijetha Badami*, V. Yoshna Sree, Juveria Masreen, Kanukurthi Meghana & C. Sahithi Priya
Affiliation
Department of Conservative Dentistry and Endodontics, MNR Dental College and Hospital, Sangareddy, Telangana, India; *Corresponding author
G. Sanjana Reddy - E-mail: g.sanjanareddy17@gmail.com
Vijetha Badami - E-mail: vijetha.mds@gmail.com
V. Yoshna Sree - E-mail: yoshnasree17@gmail.com
Juveria Masreen - E-mail: drjuveriamasreen@gmail.com
Kanukurthi Meghana - E-mail: kanukurthimeghana@gmail.com
C. Sahithi Priya - E-mail: chavva.sahithi@gmail.com
Article Type
Research Article
Date
Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026
Abstract
The optimal vehicle for enhancing the ion release and alkalinity of nano-calcium hydroxide remains unclear in endodontic therapy. Therefore, it is of interest to evaluate the effects of distilled water, propylene glycol, nano-chitosan and chlorhexidine as vehicles for nano calcium hydroxide in 60 extracted single-rooted teeth. Calcium ion release and pH were measured at 24 hours, 7 days and 15 days. Propylene glycol showed the highest and most sustained calcium ion release and alkalinity, while nano-chitosan exhibited a controlled release pattern. Thus, data shows the choice of vehicle significantly influences the physicochemical performance of nano calcium hydroxide and may affect its antimicrobial potential.
Keywords
Chitosan, calcium ion release, intracanal medicament, nano calcium hydroxide, pH and propylene glycol
Citation
Reddy et al. Bioinformation 22(8): 4737-4741 (2026)
Edited by
Ritik Kashwani
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
