Title

Comparative evaluation of apical microleakage in root canals obturated using different bio ceramic sealers: An in vitro study

Authors

Mohd Zeeshan Ahmad¹, Neha Singh^2,*, Anusha Chadhive³, Hetal Khuva⁴, Vijaya Priyadarshini⁵ & Ankit Sharma⁶

Affiliation

¹Department of Conservative Dentistry & Endodontics, Rama Dental College Hospital & Research Centre, Kanpur, Uttar Pradesh, India; ²Department of Conservative Dentistry and Endodontics, IMS, BHU, Varanasi, Uttar Pradesh, India; ³Department of Conservative Dentistry and Endodontics, Anil neerukonda institute of dental sciences, Visakhapatnam, Andhra Pradesh, India; ⁴Department of Conservative Dentistry and Endodontics, Hazaribag College of Dental Sciences and Hospital, Hazaribag, Jharkhand, India; ⁵Department of Dentistry, Clinical Cancer Trial Researcher, Institute of Cancer Research, London, England; ⁶Department of Conservative Dentistry and Endodontics, Awadh Dental College And Hospital Jamshedpur, Jharkhand, India; *Corresponding author

Email

Mohd Zeeshan Ahmad - E-mail: askzeeshan9@gmail.com
Neha Singh - E-mail: drneha2593@gmail.com
Anusha Chadhive - E-mail: chadhiveanusha@gmail.com
Hetal - E-mail: endodontist.hetal@gmail.com
Vijaya Priyadarshini - E-mail: vpvijaya@gmail.com
Ankit Sharma - E-mail: dr.ankitsharma1987@gmail.com

Article Type

Research Article

Date

Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026

Abstract

Achieving an effective and durable apical seal remains a major challenge in endodontic treatment and is critical for long-term treatment success. Therefore, it is of interest to evaluate the apical microleakage among root canals obturated with different bioceramic sealers. Apical sealing ability was assessed to determine the effectiveness of each sealer in minimizing leakage. The results showed that bioceramic sealers exhibited superior sealing performance compared with conventional resin-based sealers, with EndoSequence BC Sealer showing the least microleakage. Thus, data show the sealing efficacy of bioceramic sealers, supporting their use for improving the predictability and success of endodontic therapy.

Keywords

Apical microleakage, bioceramic sealer, EndoSequence BC sealer, root canal obturation, stereomicroscope

Citation

Ahmad et al. Bioinformation 22(8): 4742-4746 (2026)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.