Title

Linking CRP and D-dimer levels in hypertensive versus non-hypertensive COVID-19 patients at a tertiary hospital: A retrospective cross-sectional study

Authors

Akanksha Srivastava¹, Anuradha Bharosay^2,* & Nitu Choudhary³

Affiliation

¹Department of Biochemistry, Government Doon Medical college and hospital Dehradun, Uttarakhand, India; ²Department of Biochemistry, GBCM, RBB Subharti University Dehradun, Uttarakhand, India; ³Department of Biochemistry, Soban Singh Jeena Government Institute of Medical Science & Research, Almora, Uttarakhand, India; *Corresponding author

Email

Akanksha Srivastava - E-mail: srivastavaakanksha0711@gmail.com; Phone: +91 8057675656
Anuradha Bharosay - E-mail: bharosayanuradha@gmail.com; Phone: +91 9179314919
Nitu Choudhary - E-mail: niturewar7@gmail.com; +91 9711767548

Article Type

Research Article

Date

Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026

Abstract

COVID-19 pandemic has caused global disruption to the normal way of life and health conditions at the start of 2020, leaving a lasting and memorable impression on the world. Inflammatory biomarkers like C-reactive protein (CRP) and D-dimer are measured to asses inflammation and clotting risk in this severe disease and together they can help in predicting complications and guide treatment decisions. Patients were categorised as hypertensive (n=19) and non-hypertensive (n=131), out of total 150 COVID-19 positive individuals in our study, with a higher proportion of non-hypertensive patients experiencing milder symptoms. CRP and D dimer levels were found to be significantly higher in hypertensive COVID-19 patients in comparison to non-hypertensive groups (p< 0.05). Thus, data shows the importance of monitoring inflammatory biomarkers in COVID-19 positive patients with comorbidities for early identification of disease progression and targeted therapeutic interventions.

Keywords

Coronavirus disease (COVID-19), C-reactive protein (CRP), hypertension, inflammation, coagulation, pathophysiology

Citation

Srivastava et al. Bioinformation 22(8): 4759-4762 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.