Title

Efficacy of nanocoated implant surfaces in osseointegration

Authors

S. Ramesh Raja^1,*, Saloni Bharti², P. Gladys Tryphena³, Mohit Bansal⁴, Rahul Maurya⁴ & S Aswathi⁵

Affiliation

¹Department of Prosthodontics, Rajas Dental College and Hospital, Kavalkinaru, Tirunelveli, India; ²Department of Dentistry, ESIC Medical College and Hospital, Bihta, Patna, India; ³Department of Periodontics, Madha Dental College and Hospital Kundrathur, Chennai, Tamil Nadu, India; ⁴Department of Periodontology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India; ⁵Department of Periodontics, KMCT Dental College, Mukkam, Calicut, Kerala, India; *Corresponding author

Email

S. Ramesh Raja - E-mail: ramsking80@gmail.com; Phone: +91 9159397860
Saloni Bharti - E-mail: drsalonibharti2424@gmail.com; Phone: +91 7091655625
P. Gladys Tryphena - E-mail: tryphenagladys@gmail.com; Phone: +91 7845052749
Mohit Bansal - E-mail: bansalmohit877@gmail.com; Phone: +91 8076259412
Rahul Maurya - E-mail: rahulmaurya007.rockstar@gmail.com; Phone: +91 7355942079
S. Aswathi - E-mail: aswathisujil@gmail.com; Phone: +91 9895529513

Article Type

Research Article

Date

Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026

Abstract

The goal of ensuring predictable and fast integration of the ossicles, especially in compromised bone situations, demands the never ending growth in dental implant surface technology. Therefore, it is of interest to assess the clinical effectiveness of a novel nano hydroxyapatite/zirconia (n-HA/ZrO2) coated implant surface against a conventional sandblasted, large-grit, acid-etched (SLA) one. Hence, eighty-six patients participated in having a test (n-HA/ZrO2) or control (SLA) implant in the mandible under the arch with results measured in terms of implant stability and marginal bone levels at six months. The nanocoated group had much higher Implant Stability Quotient (ISQ) at 3 and 6 months (p<0.001) and also much lower mean marginal bone loss (p<0.001). Thus, data shows that n-HA/ZrO2 nanocoated surface proves to be very effective in the promotion of early outcomes of the osseointegration process, which results in the achievement of good implant stability and preservation of the peri-implant bone.

Keywords

Dental implants (DI), osseointegration, nano coating, hydroxyapatite, zirconia, randomized controlled trial (RCT)

Citation

Raja et al. Bioinformation 22(8): 4882-4886 (2026)

Edited by

Rashmi Laddha

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.