Title
Evaluating the role of platelet-rich plasma in enhancing osseointegration for dental implants
Authors
Gauravi Jain1,*, Pradnya Wagh2, Amit Kumar Upadhyay3, Karandeep Singh4, Mugur Basavanna Jayaprakash5 & Divya Soman6
Affiliation
1Department of Dentistry, LN Medical College, Bhopal, Madhya Pradesh, India; 2Department of Periodontics and Oral Implantology, Tatyasaheb Kore Dental College and Research Centre, Kolhapur, Maharashtra, India; 3Department of Periodontology, Shri Balaji Institute of Dental Sciences, Raipur, Chhattisgarh, India; 4Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India; 5Department of Prosthodontics, Dental Institute, Rajendra Institute of Medical Sciences (RIMS), Ranchi, Jharkhand, India; 6Department of Periodontics, Sri Sankara Dental College, Vennicode, Varkala, Thiruvananthapuram, Kerala, India; *Corresponding author
Gauravi Jain - E-mail: drgauravijain@gmail.com
Pradnya Wagh - E-mail: drpradnyaperiodontics999@gmail.com
Amit Kumar Upadhyay - E-mail: amitu54@gmail.com
Karandeep Singh - E-mail: karandeepsingh_fdsc@sgtuniversity.org
Mugur Basavanna Jayaprakash - E-mail: drjayaprakash2025@gmail.com
Divya Soman - E-mail: drdivyasoman@gmail.com
Article Type
Research Article
Date
Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026
Abstract
Dental implant longevity depends on osseointegration, yet Platelet-Rich Plasma (PRP)'s inconsistent clinical efficacy stems from preparation variability and heterogeneous study designs despite promising growth factor-mediated osteogenesis. Therefore, it is of interest to examine the PRP effects on implant stability and peri-implant bone in 80 patients randomized to PRP versus control groups, with serial clinical and radiographic assessments. PRP delivers bioactive proteins including VEGF, PDGF and TGF-β essential for angiogenesis and bone regeneration around implant surfaces. Heterogeneity in PRP protocols contributes to mixed literature results on bone-to-implant contact enhancement and primary stability improvement. Thus, data shows the standardizing PRP application to clarify its definitive role in accelerating osseointegration for optimizing clinical implant protocols.
Keywords
Platelet-rich plasma (PRP), dental implants, osseointegration, bone regeneration, implant stability, growth factors
Citation
Jain et al. Bioinformation 22(8): 4895-4899 (2026)
Edited by
Vini Mehta
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
