Title

Efficacy of pomegranate extract enriched mouthwash versus chlorhexidine mouthwash for plaque and gingivitis control: Randomized clinical trial

Authors

Manika Rawat^1,*, Pradeep Tangade¹, Vikas Singh¹, Ankita Jain¹, Rudraksh Pant², Gaurav Kumar¹ & Swayam Sourav Tripathy¹

Affiliation

¹Department of Public Health Dentistry, Teerthanker Mahaveer Dental College and Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India; ²Department of Oral and Maxillofacial Surgery, Teerthanker Mahaveer Dental College and Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India; *Corresponding author
 

Email

Manika Rawat- E-mail: rawatmanika@gmail.com; Phone: +91-9999613125
Pradeep Tangade - E-mail: drpradeeptangade.dental@tmu.ac.in
Vikas Singh - E-mail: drvikas.dental@tmu.ac.in
Ankita Jain - E-mail: ankitajain.0815@gmail.com
Rudraksh Pant - E-mail: rudrakshpant@gmail.com
Gaurav Kumar - E-mail: gauravgupta27121992@gmail.com
Swayam Sourav Tripathy- E-mail: swayamsouravtripathy95@gmail.com

Article Type

Research Article

Date

Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026

Abstract

Chlorhexidine mouthwash has been associated with discoloration of teeth and altered taste. Hence, 20 participants were randomly divided into two groups: Group A pomegranate peel extract mouthwash; Group B 0.2% chlorhexidine mouthwash. The Loe-Silness Gingival Index and the Turesky-Gilmore Modified Quigley-Hein Plaque Index were assessed at baseline, day 14 and day 21. The group using pomegranate extract mouthwash showed a greater improvement in the gingivitis index on days 14 (p = 0.009) and 21(p<0.05). Pomegranate extract mouthwash was more effective in reducing inflammation of the gingival. It can be used as an adjunct therapy in the prevention of gingival diseases.

Keywords

Chlorhexidine (CHX), gingivitis, mouthwash, plaque, pomegranate, P. granatum

Citation

Rawat et al. Bioinformation 22(8): 5173-5178 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.