Title

Salivary pH and oxidative stress levels among peri-implantitis patients

Authors

Veena Kalburgi^1,*, Shraddha Rani², Surbhi Saxena³, Ankit Raghuwanshi⁴, Rupal Saxena⁵ & Pratyushman Hazarika⁶

Affiliation

¹Department of Periodontology, People's College of Dental Sciences and Research Centre, People's University, Bhopal, Madhya Pradesh, India; ²Department of Dentistry, Patna Medical College and Hospital, Patna, Bihar, India; ³Department of Periodontology, People's College of Dental Sciences and Research Centre, People's University, Bhopal, Madhya Pradesh, India; ⁴Department, Bachelor of Engineering, Samrat Ashok Technological Institute, Vidisha, Madhya Pradesh, India; ⁵Department of Conservative Dentistry and Endodontics, People's College of Dental Sciences and Research Centre, People's University, Bhopal, Madhya Pradesh, India; ⁶Department of Prosthodontics and Crown and Bridge, Government Dental College, Dibrugarh; *Corresponding author

Email

Veena Kalburgi - E-mail: drveenakalburgi1@gmail.com
Shraddha Rani - E-mail: shraddha.bds@gmail.com
Surbhi Saxena - E-mail: saxenasurbhi996@gmail.com
Ankit Raghuwanshi - E-mail: ankitraghuwanshi13@gmail.com
Rupal Saxena - E-mail: rupal.saxena1703@gmail.com
Pratyushman Hazarika - E-mail: pratyushman@gmail.com

Article Type

Research Article

Date

Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026

Abstract

Dental implants are a dependable treatment for tooth replacement, but peri-implant infections can compromise long-term treatment success. This comparative study evaluated 60 patients, equally divided into peri-implant health, peri-implant mucositis, and peri implantitis groups, by assessing clinical peri-implant parameters, salivary pH, malondialdehyde, and total antioxidant capacity. Patients with peri-implantitis showed higher plaque index, bleeding on probing, probing depth, marginal bone loss, and malondialdehyde levels, with lower salivary pH and total antioxidant capacity. These findings indicate an association between peri implant disease and altered salivary pH and oxidative stress status. Thus, data shows that salivary pH and oxidative stress markers as potential adjunctive tools for early assessment of peri-implant disease.

Keywords

Dental implants, peri-implantitis, peri-implant mucositis, salivary pH, oxidative stress, malondialdehyde, total antioxidant capacity

Citation

Kalburgi et al. Bioinformation 22(8): 5275-5280 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.