Title

Hyperbaric ropivacaine versus bupivacaine for spinal anesthesia in lower limb orthopedic surgery: A double-blind randomized controlled trial

Authors

Pavan Singh Rahangdale^1*, Mona Bhalavi¹, Shubham Rahul Rai¹ & Sucheta Tidke²

Affiliation

¹Department of Anaesthesiology, Government Medical College, Seoni, Madhya Pradesh, India; ²Department of Anaesthesiology, MGIMS, Sevagram, Maharashtra, India; *Corresponding Author

Email

Pavan Singh Rahangdale - E-mail: drpavansingh0609@gmail.com
Mona Bhalavi - E-mail: monabhalavi@gmail.com
Shubham Rahul Rai - E-mail: raishubhamrahul@gmail.com
Sucheta Tidke - E-mail: drpavansingh09@gmail.com

Article Type

Research Article

Date

Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026

Abstract

Spinal anesthesia is commonly used for lower limb orthopedic surgery because it provides rapid onset, reliable sensory and motor blockade, reduced blood loss, and good postoperative analgesia. Hence, this randomized double-blinded controlled trial compared hyperbaric ropivacaine 18 mg with hyperbaric bupivacaine 18 mg in 80 ASA I and II adults undergoing elective lower limb orthopedic surgery under spinal anesthesia, with 40 patients in each group. Hyperbaric bupivacaine produced a faster onset and longer duration of sensory and motor blockade, whereas ropivacaine allowed earlier motor recovery and better intraoperative hemodynamic stability, with fewer episodes of hypotension and bradycardia. Both agents provided satisfactory surgical anesthesia with acceptable block quality. Thus, we show that hyperbaric ropivacaine is a useful alternative to bupivacaine when shorter motor blockade and greater cardiovascular stability are preferred.

Keywords

Hyperbaric ropivacaine, hyperbaric bupivacaine, spinal anesthesia, orthopedic surgery, sensory blockade, motor blockade, hemodynamic stability.

Citation

Rahangdale et al. Bioinformation 22(8): 5325-5330 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.