Title
Comparative evaluation of autologous sticky bone and leukocyte platelet-rich fibrin block in intrabony defects
Authors
Vithika Pandey*, Ravi Madan, Ankita Mutt, Deiji Bora, Shashwat Asthana & Shaleen Varshney
Affiliation
Departments of Periodontology and Prosthodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh, India; *Corresponding author
Vithika Pandey - E-mail: pvini1998@gmail.com
Ravi Madan - E-mail: ellorabhattmadan@gmail.com
Ankita Mutt - E-mail: drankitaperio258@gmail.com
Deiji Bora - E-mail: itzdeijiborahere96@gmail.com
Shashwat Asthana E-mail: adrshashwat@gmail.com
Shaleen Varshney - E-mail: shaleenvarshney0805@gmail.com
Article Type
Research Article
Date
Received August 1, 2026; Revised August 31, 2026; Accepted August 31, 2026, Published August 31, 2026
Abstract
Periodontal intrabony defects require regenerative approaches and platelet-rich fibrin formulations can deliver growth factors while stabilizing particulate graft material. Therefore, it is of interest to compare the autologous sticky bone with a leukocyte platelet-rich fibrin (L-PRF) block in 30 intrabony defect sites randomized equally between the two treatments and assessed clinically and by CBCT. Probing pocket depth and clinical attachment level were recorded at baseline, 3 months and 6 months, while crestal level and bone fill were evaluated at baseline and 6 months. Both groups showed significant improvements in gingival index, probing depth and attachment level over time, with comparable intrabony defect reduction, bone fill and crestal-level changes and no significant intergroup differences. Sticky bone and L-PRF block therefore produced similar six-month clinical and radiographic improvements in the treatment of intrabony periodontal defects.
Keywords
Intrabony defects; sticky bone; leukocyte-platelet rich fibrin block; xenograft; periodontal regeneration; bone fill; crestal level
Citation
Pandey et al. Bioinformation 22(8): 5401-5405 (2026)
Edited by
Hiroj Bagde
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
