Title
Decoding odontogenic keratocysts: A retrospective radiographic study
Authors
Tejaswi Katne, Srikanth Goud Gotoor*, Ramlal Gantala, Rashmitha Arutla, K. Sai Susmitha & M. Nikhitha
Affiliation
Department of Oral Medicine and Radiology, SVS Institute of Dental Sciences, Mahabubnagar, Telangana, India; *Corresponding author
Tejaswi Katne - E-mail: tejaswikatne@gmail.com
Srikanth Goud Gotoor - E-mail: drskanth.g@gmail.com
Ramlal Gantala - E-mail: ramlalgantala12@gmail.com
Rashmitha Arutla - E-mail: rashmitha.arutla@gmail.com
K. Sai Susmitha - E-mail: saisusmitakura93@gmail.com
M. Nikhitha - E-mail: nikhithamaheshwaram96@gmail.com
Article Type
Research Article
Date
Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026
Abstract
Odontogenic keratocysts display aggressive growth and variable CBCT appearances that can overlap with other jaw cysts and tumors, complicating radiographic characterization and surgical planning. Therefore, it is of interest to evaluate the demographic distribution, anatomical location, internal architecture, radiographic variants, lesion borders, dimensional profile and effects on adjacent structures in 39 histopathologically confirmed odontogenic keratocysts using archival CBCT examinations. Categorical features were summarized descriptively, a standardized smaller-to-larger dimension ratio was calculated from the largest documented lesion pair and associations between internal structure and adjacent-structure effects were tested using Fisher’s exact test. The cohort included 23 males and 16 females (mean age 30.0 ± 15.6 years); 28 cases involved the mandible alone, 7 the maxilla alone and 4 both jaws, while multilocular architecture, cortical expansion, inferior alveolar canal involvement and tooth displacement were observed in 66.7%, 94.9%, 69.2% and 53.8%, respectively, with no significant adjacent-structure difference by locularity (all p>0.05). Thus, CBCT provided clinically important three-dimensional information, but no single imaging sign, including locularity or dimensional ratio, was sufficiently specific to replace histopathological confirmation.
Keywords
Odontogenic keratocyst (OKC), cone-beam computed tomography (CBCT), radiographic variants, inferior alveolar canal, cortical expansion, multilocular lesion
Citation
Katne et al. Bioinformation 22(9): 5611-5615 (2026)
Edited by
Ashwini Dhopte
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
