Title

Clinicopathological correlation in patients with oral squamous cell carcinoma

Authors

Manusmrati Mishraš, Sonia Agarwal², Vinod Sargaiyan¹, Vaibhavi Mehta³, Gourav Saini⁴ & Tanvi Hirani⁵

Affiliation

¹Department of Oral Pathology and Microbiology, Maharana Pratap College of Dentistry and Research Centre, Gwalior, Madhya Pradesh, India; ²Department of Pathology, Mahatma Gandhi Medical College and Hospital, Sitapura, Jaipur, Rajasthan, India; ³Department of Oral Medicine and Radiology, K M Shah Dental College and Hospital, Sumandeep Vidyapeeth (Deemed to be University), Vadodara, Gujarat, India; ⁴Department of Oral and Maxillofacial Pathology and Oral Microbiology, SGT Dental College and University, Budhera, Gurugram, Haryana, India; ⁵Department of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India; *Corresponding author

Email

Manusmrati Mishra - E-mail: manusmratimpurohit@gmail.com
Sonia Agrawal - E-mail: soniamgmch@gmail.com
Vinod Sargaiyan - E-mail: dr.vinodsargaiyan@yahoo.co.in
Vaibhavi Mehta - E-mail: vaibhavishukla69@gmail.com
Gourav Saini - E-mail: gouravsaini89366@gmail.com
Tanvi Hirani - E-mail: tanvimehta@karnavatiuniversity.edu.in

Article Type

Research Article

Date

Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026

Abstract

Early diagnosis of oral squamous cell carcinoma is essential to improve prognosis and reduce disease-related morbidity and mortality. Therefore, it is of interest to evaluate the association between clinical presentation and histopathological findings in 100 patients with histopathologically confirmed oral squamous cell carcinoma. Demographic characteristics, risk factors, tumor site, clinical stage, and histological grade were analyzed to identify clinicopathological correlations. Statistical analysis revealed significant associations between clinical and pathological variables, highlighting their value in disease assessment. Thus integrated clinical and histopathological evaluation facilitates early diagnosis, treatment planning, and improved outcomes in oral squamous cell carcinoma.

Keywords

Oral squamous cell carcinoma, clinicopathological correlation, risk factors, histopathology, grading, staging

Citation

Mishra et al. Bioinformation 22(9): 5668-5673 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.