Title

Hypoalbuminemia: A poor prognostic harbinger in diabetic ketoacidosis

Authors

VinayVerma^1,*, Bhanpratap Ahirwar¹, Shivam Chaudhary¹, Sachin Parmar² & Asha Mishra²

Affiliation

¹Deparment of General Medicine, V.K.S. Government Medical College, Neemuch, Madhya Pradesh, India; ²Deparment of Community Medicine, V.K.S. Government Medical College, Neemuch, Madhya Pradesh, India; *Corresponding author

Email

Vinay Verma - E-mail: vinayverma522@gmail.com
Bhanpratap Ahirwar - E-mail: bhanahirwar5@gmail.com
Shivam Chaudhary - E-mail: sc23596@gmail.com
Sachin Parma - E-mail: dr.sachinparmar@gmail.com
Asha Mishra - E-mail: ashadubey86@gmail.com

Article Type

Research Article

Date

Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026

Abstract

The incidence of DKA at the global level has been reported to be between 0 and 56 episodes per 1000 person-year in people with diabetes depending on the population and setting. Diabetes ketoacidosis (DKA) is a life-threatening emergency disease with high mortality in resource-restricted areas and 50 cases (2019-2021) of Acharya Vinoba Bhave Rural Hospital, Wardha, and ICU were compared to 50 diabetic controls. The patients in the DKA group had a reduced serum albumin; the non-survivors had even less (2.56 ±1.07 versus 3.40 ±0.65 g/dL; p=0.040). Regression established that albumin was not only an independent predictor of mortality (OR 6.069; 95% CI -1.149-8.010; p=0.045). High-risk patients can be detected during routine, simple albumin testing at the time of admission and directed towards higher degrees of treatment.

Keywords

Diabetic ketoacidosis (DKA), serum albumin, prognostic marker

Citation

Verma et al. Bioinformation 22(9): 5742-5746 (2026)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.