Title
Prevalance of Neuroendocrine tumours among patients at a tertiary centre in India
Authors
Javid Ahmad Peer*, Shikhar Tripathi, Subhashish Das, Suvendu Sekhar Jena, Amitabh Yadav, Bijoy Lakshmi Chutia & Samiran Nundy
Affiliation
Department of Surgical Gastroenterology, GI & HPB Onco-surgery and Liver Transplantation, Sir Ganga Ram Hospital, New Delhi, India; *Corresponding author
Javid Ahmad Peer - E-mail: drjavid16@gmail.com
Shikhar Tripathi - E-mail: shikhartripathi@gmail.com
Subhashish Das - E-mail: subhamsubham1@yahoo.co.in
Suvendu Sekhar Jena - E-mail: suvu1078@gmail.com
Amitabh Yadav - E-mail: amitabhyadav99@gmail.com
Bijoy Lakshmi Chutia - E-mail: bijoylakshmichutia001@gmail.com
Samiran Nundy - E-mail: snundy@hotmail.com
Article Type
Research Article
Date
Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026
Abstract
Neuroendocrine tumours (NETs) are uncommon neoplasms with heterogeneous anatomical distribution; grading and clinical behaviour and large institutional series from India remain limited. We retrospectively analysed prospectively maintained data for 117 patients diagnosed and treated for NETs at a tertiary-care centre from January 2010 to December 2022, assessing anatomical site, WHO grade, immunohistochemistry and early follow-up. Most tumours involved the gastrointestinal tract (65.8%), followed by the hepatopancreatobiliary region (33.3%); grade 1 tumours were most frequent (51.3%), while grade 3 disease remained common (29.1%) and Ki-67 index correlated strongly with mitotic count (r = 0.82, p < 0.001). Indian NETs in this cohort showed an upper gastrointestinal and periampullary/pancreatic clustering with a substantial high-grade burden at presentation, supporting earlier endoscopic evaluation, wider functional imaging access and multidisciplinary care.
Keywords
Neuroendocrine tumours (NETs), gastrointestinal neuroendocrine tumours, hepatopancreatobiliary neuroendocrine tumours, Ki-67 index
Citation
Peer et al. Bioinformation 22(9): 5751-5755 (2026)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
