Title

Comparative analysis of HbA1c level among patients with non-diabetic iron deficiency anemia

Authors

Surumi Azees¹, M. Dhanuthra ²,*& Numan A. Mandaty¹

Affiliation

¹Department of General Medicine, Amrita Institute of Medical Sciences & Research Centre, Amrita Vishwa Vidyapeetha, Kochi, Kerala, India; ²Department of General Medicine, KIMS Avitis Hospital, Nenmara, Palakkad, Kerala, India; *Corresponding author

Email

Surumi Azees - E-mail: 1991surumiazees@gmail.com
M. Dhanuthra - E-mail: dhanuthra@gmail.com
Numan A. Mandaty - E-mail: numanam24@gmail.com

Article Type

Research Article

Date

Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026

Abstract

Iron deficiency anaemia (IDA) alters haemoglobin A1C (HbA1c) independently of glucose, distorting glycaemic assessments in non diabetics. Therefore, it is of interest to compare the HbA1c levels and haematological parameters among 50 non-diabetic patients with IDA and 50 non-IDA subjects. The IDA group showed significantly lower haemoglobin, mean corpuscular volume (MCV), serum iron, and ferritin (p<0.001). A substantial negative correlation linked HbA1c to these iron parameters, indicating that worsening IDA increases HbA1c. Clinicians must account for IDA during HbA1c interpretation to prevent the misdiagnosis of prediabetes or diabetes.

Keywords

Glycated haemoglobin, iron deficiency anaemia (IDA), iron profile, non-diabetic patients, serum ferritin

Citation

Azees et al. Bioinformation 22(9): 5879-5883 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.