Title
Comparative diagnostic performance of conventional and modified gram staining versus culture for urinary tract infection: A protocol
Authors
Swati Narayan Thakare & Dhruba Chandi*
Affiliation
Department of Microbiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, Maharashtra, India; *Corresponding author
Swati Narayan Thalare - E-mail: tswati24@gmail.com
Dhruba Chandi - E-mail: dhruba.chandi@dmiher.edu.in
Article Type
Research Article
Date
Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026
Abstract
Urinary tract infections (UTIs) require rapid diagnostics to guide early empiric therapy and avoid culture delays. This prospective cross-sectional study will comparatively evaluate 330 suspected UTI urine samples in a tertiary care setting. We will determine the sensitivity and specificity of conventional versus modified Gram staining against quantitative culture. Modified Gram staining of centrifuged deposits is hypothesized to show superior diagnostic accuracy over conventional methods. This fast, cost-effective screening technique aims to improve timely clinical decision-making and antibiotic stewardship.
Keywords
Urinary tract infection (UTI), gram staining, diagnostic effectiveness, urine culture, modified gram stain, sensitivity and specificity
Citation
Thakare & Chandi Bioinformation 22(9): 5913-5915 (2026)
Edited by
Rashmi Laddha
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
