Title

Comparative study of radicular cyst and dentigerous cyst: Clinical and histological correlation

Authors

Prerna Aggarwal¹, P Kanchan Malawat², Harveen Singh³, Astha Chaudhry⁴, Rahul Raviraj Shetty⁵,*, Manpreet Kaur⁶ & Tanvi Hirani⁷

Affiliation

¹Department of Oral and Maxillofacial Pathology, Genesis Institute of Dental Sciences and Research, Ferozepur, Punjab, India; ²Department of Dentistry, Sardar Patel Medical College, Bikaner, Rajasthan, India; ³Department of Periodontology, Punjab Government Dental College and Hospital, Amritsar, Punjab, India;⁴Department of Oral Medicine and Radiology, Faculty of Dental Sciences, SGT University, Gurugram, Haryana, India; ⁵Department of Oral Medicine and Radiology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Navi Mumbai, Maharashtra, India; ⁶Department of Dentistry, Wellington Dental, Guelph, Ontario, Canada; ⁷Department of Periodontology and Implantology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India; *Corresponding author

Email

Prerna Aggarwal - E-mail: aggarwalprerna94@gmail.com; Phone: +91 9780644108
P Kanchan Malawat - E-mail: kanchanpanwar15@gmail.com
Harveen Singh - E-mail: veenu61183@gmail.com; Phone: +91 9888813133
Astha Chaudhry - E-mail: astha.chaudhry@sgtuniversity.org; Phone: +91 9711807733
Rahul Raviraj Shetty - E-mail: drrahulrshetty@gmail.com
Manpreet Kaur - E-mail: smileslifetime@gmail.com
Tanvi Hirani- Email: tanvimehta@karnavatiuniversity.edu.in

Article Type

Research Article

Date

Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026
 

Abstract

Radicular and dentigerous cysts are common odontogenic cysts with overlapping clinical and radiographic features that may complicate diagnosis. This comparative study evaluated 150 histopathologically confirmed cases, including 90 radicular and 60 dentigerous cysts, for their clinical, radiographic and histopathological characteristics. Radicular cysts predominated in the third to fifth decades and showed hyperplastic non-keratinized stratified squamous epithelium with dense inflammation, whereas dentigerous cysts occurred more often in younger patients and commonly involved mandibular third molars. A significant correlation was observed between radiographic appearance and histopathological features. These findings emphasize integrated clinical, radiographic and histopathological assessment for accurate odontogenic cyst diagnosis and appropriate treatment planning.

Keywords

Radicular cyst, dentigerous cyst, odontogenic cysts, histopathology, clinicopathological correlation, jaw lesions

Citation

Aggarwal et al. Bioinformation 22(9): 6031-6035 (2026)

Edited by

Vini Mehta

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.