Title

Levobupivacaine with fentanyl or dexmedetomidine for lower limb surgery: A randomized comparative study

Authors

Ankita Das*, Supriya Kar & Sapna Das

Affiliation

Department of Anaesthesiology, Kalinga Institute of Medical Sciences, Kalinga Institute of I1ndustrial Technology (KIIT), Bhubaneswar, Odisha, India; *Corresponding author

Email

Ankita Das - E-mail: ankita.das@kims.ac.in
Supriya Kar - E-mail: supriya.kar1@kims.ac.in
Sapna Das - E-mail: sapna.das@kims.ac.in

Article Type

Research Article

Date

Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026
 

Abstract

Epidural adjuvants improve block quality and prolong post-operative analgesia in lower limb surgery. Therefore, it is of interest to compare the epidural levobupivacaine with fentanyl or dexmedetomidine in 84 ASA I–II patients. Sensory and motor block onset, haemodynamics, analgesia duration and complications were evaluated. Dexmedetomidine produced faster block onset and longer analgesia than fentanyl (p < 0.0001), with comparable haemodynamics. Thus, dexmedetomidine is a superior epidural adjuvant to levobupivacaine for lower limb surgery, providing faster block onset and prolonged analgesia.

Keywords

Dexmedetomidine, epidural anesthesia, fentanyl, levobupivacaine, post-operative pain

Citation

Das et al. Bioinformation 22(9): 6081-6085 (2026)

Edited by

Ruby Singh

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.