Title

Effect of dentin biomodifiers on shear bond strength and dentin-resin interface: An in vitro study

Authors

Shazeena Qaiser¹,*, Darshana Devadiga², Mithra N. Hegde²

Affiliation

¹Department of Conservative Dentistry and Endodontics, Dr Qaiser’s Dental Clinic, Srinagar, India; ²Department of Conservative Dentistry and Endodontics, AB Shetty Memorial Institute of Dental Sciences (ABSMIDS), NITTE (Deemed to be University), Mangaluru, India; *Corresponding author

Email

Shazeena Qaiser - E-mail: shazeena.q18@gmail.com
Darshana Devadiga - E-mail: drdarshanadevadiga@nitte.edu.in
Mithra N. Hegde - E-mail: drmithra.hegde@nitte.edu.in

Article Type

Research Article

Date

Received September 1, 2026; Revised September 30, 2026; Accepted September 30, 2026, Published September 30, 2026
 

Abstract

Durable adhesion to dentin remains essential for the long-term success of adhesive restorations. Therefore, it is of interest to compare the effects of 6.5% grape seed extract (GSE), casein phosphopeptides–amorphous calcium phosphate (CPP-ACP) and their combination on dentinal shear bond strength and the resin–dentin interface. Shear bond strength was measured using a universal testing machine and the resin–dentin interface was evaluated by scanning electron microscopy. Significant differences were observed among the groups (p < 0.001), with GSE showing the highest shear bond strength (3.39 MPa), greatest resin tag score and longest resin tags (70.20 µm). Thus, data shows the use of dentin biomodifiers, particularly GSE, to enhance dentin bonding and guide evidence-based adhesive pre-treatment strategies.

Keywords

Casein phosphopeptides–amorphous calcium phosphate (CPP-ACP), grape seed extract (GSE), resin tags, scanning electron microscopy (SEM), shear bond strength (SBS)

Citation

Qaiser et al. Bioinformation 22(9): 6112-6115 (2026)

Edited by

Ritik Kashwani

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.