Dr. P. KANGUEANE

Executive Director, Biomedical Informatics

Professor, Bioinformatics & Biotechnology

Founding Editor & Chief, Bioinformation, India

Associate Editor, BMC Bioinformatics, UK

Founder, Post Genetics Society, USA

Managing Editor, Frontiers in Bioscience, USA

President, Biomedical Informatics Society

E-mail: kangueane{at}bioinformation.net

E-mail: kangueane{at}gmail.com

http://network.nature.com/profile/kangueane

https://www.facebook.com/kangueane

         

 
 
 
 
 
 
 
 
 

 

 

DOB: November 09, 1974

 

Google: Kangueane

 

EDUCATION (1993-2001):

Ph.D., NUS, Bioinformatics & Immunology, 1998-2001

B.Tech., Anna University, Industrial Biotechnology, 1993-1997

 

PROFESSIONAL EXPERIENCE (2001-2013):

2011 (May) - Current, CEO, Biomedical Informatics, India

2009 (Apr) - 2011 (Apr), Professor, Bioinformatics, AIMST University, Malaysia

2007 (Dec) - current, Professor (Visiting), Bioinformatics & Biotechnology, VITU, India

2009 (Apr) - Advisor, Biomedical Informatics Network, India
2006 (Aug) - 2009 (Apr), Managing Director, Biomedical Informatics, India

2007 (Dec) - current, President, Biomedical Informatics Society, India

2006 (Aug) - 2009 (Apr), Director, Biomedical Informatics, India

2002 (Jan) - 2006 (Aug), Assistant Professor, Bioinformatics & Biotechnology, NTU, Singapore

2001 (Feb) - 2001 (Sep), Visiting Scientist, CHIRON CORPORATION, Bioinformatics, USA

2001 (Feb) - 2001 (Nov), Scientist, S*Bio [P] Ltd, Bioinformatics, Singapore

 

HONORS, AWARDS, RESEARCH GRANTS (1991-2009):

2008-, Ambassador for Peace, Universal Peace Federation, Contribution in Science and Technology

2003-2006, 0.700 M S$, Introns-The indispensable elements in eukaryotic genomes, A*STAR, Singapore

2002-2005, 0.300 M S$, Prokaryotic architecture in eukaryotic genes, A*STAR, Singapore

1998-2002, 0.054 M S$, Research Scholarship, NUS, Singapore

1991-1991, Merit Award in Science, Ministry of Education, Government of Pondicherry, India

 

PROFESSIONAL ACTIVITIES (2002-2009):

  1. 2011, EXPERT PANEL MEMBER, MOSTI, Malaysia

  2. 2011, Executive committee member, INCOB 2011, Malaysia

  3. 2010 (July 29-30), Panel Member, MOSTI, MGI Research Projects, Malaysia

  4. 2010 (May - June) Acting Dean, Faculty of Applied Science, AIMST University, Malaysia

  5. 2010 (August), Grant reviewer, MOSTI, Malaysia

  6. 2010 (August), Panel Member, RMke10, Industrial Biotechnology, MOSTI, Malaysia

  7. 2010, Scientific advisor, Cancer Biotech Pvt. Ltd. Malaysia

  8. 2009 (May - June) Acting Dean, Faculty of Applied Science, AIMST University, Malaysia

  9. 2009,2010, Executive member, APBioNet, Singapore

  10. 2009, President and Founder, Agro Informatics Society, India

  11. 2009, Scientific advisor, Bio Design Vaccine Pvt. Ltd. Malaysia

  12. 2008, Executive Editor, Journal of Computer Science & Systems Biology, USA

  13. 2008, President and Founder, Biomedical Informatics Society, India

  14. 2008-, Board of Studies, Faculty of Technology, Anna University, Trichirappalli, India

  15. 2008-, Associate Editor, BMC Bioinformatics, United Kingdom

  16. 2007-, President and Founder, Biomedical Informatics Society, India

  17. 2007-, Session chair, International conference on biomarkers in health and environmental management, PSG College of Arts and Science, Coimbatore, India, January 10 - January 12, 2007.

  18. 2007-, External Examiner as Panel Member for oral examination, Department of Pharmacy, National University of Singapore, Singapore (February 08, 2007).

  19. 2007-, Editorial Board, Global Science Books, Japan.

  20. 2006-, Program committee, ICMMB-15th, 6-8th Dec. 2006, Singapore

  21.  2006- Founder & Executive Member, Post Genetics Society, USA,

  22. 2006, BIO Invest 2006, 17-19 November 2006, Grand Hyatt, Mumbai, India.

  23. 2006- Founder, Post Genetics Society, USA, http://www.junkdna.com/postgenetics

  24. 2005- Invited speaker 5nd VIRTUAL CONFERENCE ON BIOINFORMATICS AND GENOMICS, USA, 25 October - 28 October 2005. Invited speaker

  25. 2005-, External Examiner for Ph.D Thesis by Mr. S. RENGANATHAN, Anna University, India (July, 2005)

  26. 2005- Advisory on NSF Bioinformatics Database and Data Analysis development project PUBLIC: A Public Unified BioLogical InformatiCs Data Management and Analysis System (William Perrizo)

  27. 2005-, External Examiner for Ph.D Thesis “Studies on protein structure: Tripeptide analysis and its applications” by SHARMILA ANISHETTY, Anna University, India (February, 2005)

  28. 2005-, Academic focus coordinator, Biochemical and Biomedical Engineering, MAE, NTU

  29. 2005-, Program committee, SIG Structure APBC 2005, Singapore

  30. 2005-, Editor, Bioinformation

  31. 2004-, NTU Examiner for M. Eng Thesis “VR-Enhanced modeling and visualization of Cystine Knot proteins” by Ms. SU LI, NTU, Singapore

  32. 2004-, Managing Editor, Frontiers in Bioscience, USA

  33. 2004-, Program committee, Third International Conference on Artificial Immune Systems, Italy

  34. 2003-, Bio-safety officer, MAE, NTU

  35. 2002-, Reviewer for Bioinformatics, Nucleic Acids Research, BMC Genomics, BMC Bioinformatics, Evolutionary Bioinformatics online, Current Bioinformatics

  36. 2002-, Member, American Association for the Advancement of Science (AAAS), USA

  37. 2002-, Member, International Society for Computational Biology (ISCB), USA

  38. 2001-, Board of Directors, Biomedical Informatics, India

RESEARCH (1995-2010):

Bioinformation Technology with specialization in (1) Peptide Vaccine Design, (2) Immuno-therapeutics, (3) Molecular Evolution, (4) Enzyme Engineering, (5) Protein – protein Interactions, (6) Computational Structural Biology

 

ADVISORY ROLE IN RESEARCH (2002-2010)

GRADUATE STUDENTS (12) and Research Staff (12):

  • Dr. Zhao Bing (2002-2005) – Ph.D degree – completed (employed in Western Ontario, Canada)

  • Dr. Yu Yiting (2002-2005) – Ph.D degree – completed (employed in GIS, Singapore)

  • Dr. Li Lei (2002-2005) – Ph.D degree – completed (employed in Western Ontario, Canada)

  • Dr. Zhanhua Ciu (2002-2005) – Ph.D degree – completed (employed in China)

  • Ms. Lim Yun Ping (2002-2004) – M.S degree – completed (employed in BII, Singapore)

  • Mr. Jia Yiyu (2002-2004) – M.S degree – completed (employed in BIOPOLIS, Singapore)

  • Dr. Mohana Priya (2008 -2010), PhD degree (employed in VITU)

  • Dr. Sajitha Lu Lu (2008 -2010), PhD degree (employed in VITU)

  • Dr. Jayanthi (2008 -2010), PhD degree (employed in VITU)

  • Mr. Abishek Suresh (2010-2011), MS degree by Research  (employed in UQ, Australia)

  • Ms. G. Shamini (2010-2011), MS degree by Research (employed in Malaysia)

  • Ms. G. Sowmya (2010-2011), MS degree by Research (employed in MQ, Australia)

Thesis advised (2002-2010)

  1. Developing Bioinformatics Tools for studying Alternative Splicing in Human (Ms. Lim Yun Ping)

  2. Protein Subunit Interactions - Hetero-dimers versus Homo-dimers (Dr. Cui Zhanhua)

  3. Protein - Protein Interactions: Hot spots, side chains and LIGAND effects (Dr. Li Lei)

  4. A novel HLA-peptide binding model and HLA super-type sub-typing  (Dr. Zhao Bing)

  5. Identification, analysis, evaluation of fusion proteins of bacterial origin (Dr. Yu Yiting)

  6. Class 2 HLA-peptide binding prediction using structural principles (Dr. Mohana Priya)

  7. Insight into Homo-dimer folding and binding (Dr. Sajitha Lulu)

  8. Bioinformatics analysis of anti fungal proteins (AFP) (Dr. Jayanthi)

  9. CART assignment of homodimer folding mechanism to known structures (Abishek Suresh)

  10. Insight from mutational analysis of cholera toxin from different strains of V. cholerae (G. Shamini)

  11. Hetero-dimer protein interfaces (G. Sowmya)

ALUMNI Research Staff (12)

Nidhi Dhandona (employed with IMCB), Iti Chadurvedi (employed in NTU), Lee Pern Chern (employed with I2R), Xue Hao (employed in Singapore), Kingshuk Gosh (employed in Singapore), Kok Huiting (employed in Singapore), Rajarathinam Kayathri (Biomedical Infromatics, now married and settled), Sathish Nandagond (VITU), Abeshiek Suresh (VITU), Karthikraja Velmurugan (VITU), Bhagavathi Perumal (settled in Singapore), Ilakya (TCS, India), A. Vaishnavi (Accenture, India), Kalaivani (EBI, UK)

 

Countries traveled and presented scientific data (6)

USA (2000-2005), Russia (2005), India (2000, 2001, 2004), Singapore (1998-2005), Malaysia (2004, 2009 - 2010), Canada (2002), China (2009)

 

Countries Transited (6)

Hong Hong, Japan, Taiwan, South Korea, Sri Lanka, Dubai

 

SELECTED PRESENT/PAST COLLABORATORS/ASSOCIATES/ADVISORS

Paul Shapshak, Miami Miller Medical School, USA (HIV/NeuroAIDS 2002-2008)

Subbiah Subramanian, i-dns, USA (Bioinformatics 1998-2008)

Meena K. Sakharkar, NANYANG Technological University, Singapore (Genome Design 1998-2008)

Prassana R, Kolatkar, Genome Institute of Singapore, Singapore (Bioinformatics 1998-2006)

Pennathur Gautam, Anna University, India (Lipase Engineering 1995-2008)

Darren R. Flower, JIVR, UK (Vaccine Design 2002-2008)

Venkatarajan Subramanian Mathura, Roskamp Institute, USA (Bioinformatics 2001-2008)

Ren Ee Chee, National University of Singapore, Singapore (HLA Biology 1998-2006)

B. S. Lakshmi, Anna University, India (Biotechnology 1995-2008)

 

TEACHING EXPERIENCE (2002-2010 for a  1000+  students)

Computational Biology (M. S students, B.S students); Bioprocess and Biotechnology (B. Eng students); Computing (B.S students); Bioinformatics (M. S students), Molecular modeling and drug design (B.S students)

 

University Year

Code

Degree

Year

Semester

Subject

Lecture Hours

NTU 2002-2006

M489

B. Eng MAE

Year 4 PE

2

Biochemical and Bioprocess

19

NTU 2002-2006

M6545

M. Sc BME

Year 2 PE

1

Clinical and Comp. Biology

9

NTU 2002-2006 FE1008 B. Eng Year 1 1 C++ Computing 48
NTU 2002-2006 FE1008 B. Eng Year 1 2 C++ Computing 48
VITU 2007-2008 MPH508 M. Tech Year 1 2 Bioinformatics 50
VITU 2007-2008 5BBTE07 B. Tech Year 4 1 Mol. Mod. and Drug Design 40
VITU 2008-2009 05BIFE04 B. Tech Year 3 2 Comparative Genomics 40
AIMST 2009-2010 32108 B. S Year 2 1 Bioinformatics 40
AIMST 2009-2009 32107 B.  S Year 3 1 Genomics 10
AIMST 2009-2009 B. S Year 3 1 Biotechnology Special Topics 10
AIMST 2009-2010 33111 B. S Year 3 1 Mol. Mod. 40
AIMST 2010-2010 B. S Year 3 2 Comparative Genomics

 

COMPUTING SKILLS

PERL, C++, FORTRAN, UNIX, HTML

 

PROJECT MANAGEMENT

Effectively managed 2 funded projects supervising 24+ staff’s and students over the last 10 years.

Board of Director, Biomedical Informatics (2001 - current date)
Managing Director (2006 - current date), Biomedical Informatics, India
BIOINFORMATION, Founding Editor (2005 – till date), effectively managed the journal.

 

HOBBIES

Writing research grants in Bioinformation & Biotechnology, attending scientific meetings, debating evolutionary hypothesis

 

PUBLICATIONS (1999-2010)

TOTAL: 134; Journal papers (53); Books (3) and book chapters (29); Conference papers (50)

 Journal Publications (53)

  • P. Shapshak, P. Kangueane, R.K. Fujimura, D. Commins, F. Chiappelli, E. Singer, A. Levine, A. Minagar, F.J. Novembre, C. Somboonwit, A. Nath, J. Sinnott, Editorial NeuroAIDS Review (2010) AIDS Journal PDF

  • Suresh A, Lalitha P, Kangueane P (2010) CART Assignment of Folding Mechanisms to Homodimers with Known Structures. J Proteomics Bioinform 3: 279-285. doi:10.4172/jpb.1000152

  • Sowmya G, Vaishnai A, Kangueane P, Structure modeling based computer aided T-cell epitope design (2008) Bio-Algorithms and Med-Systems, 4(8): 5-13 (Invited opening paper) PDF

  • S. Jayanthi, N. A Udaya Prakash, P. Kangueane, Lazer Mathew, K. Sekar. Study of evolution, homology conservation and identification of unique sequence signatures in GH 19 family chitinases (2010) Journal of Molecular Evolution, (2010) 70: 466–478.

  • Vaishnai A, Sowmya G, Kalaivanii J, Ilakya S, Kangueane U, Kangueane P, Interaction modes at protein hetero-dimer interfaces (2010), BIOINFORMATION 4 (7): 310-319.

  • Mohanapriya A, Nandagond S, Shapshak P, Kangueane U., Kangueane P, A HLA-DRB supertype chart with potential overlapping peptide binding function (2010) BIOINFORMATION 4 (7): 300-309.

  • P. Kangueane, Designing Short Peptides as Viral Vaccines, (2009) J Proteomics Bioinform S3:6 ISSN: 0974-276X JPB.

  • Jayanthi M., Kangueane P., Udaya Prakash N.A., Sekar K. Influence of disulfide bonds on the conformation of the antifungal protein from Eucommia ulmoides oliver (2009) OPEN STRUCTURAL BIOLOGY JOURNAL, 3:94-103.

  • Suresh A, Karthikraja V, Lulu S, Kangueane U, Kangueane P, A decision tree model for the prediction of homodimer folding mechanism, (2009), BIOINFORMATION 4 (5): 197-205.

  • Jayanthi M., Udaya Prakash, N.A, Kangueane P, Sekar K. Effect of Disulfide Bonds in Antifungal Peptide from Petunia Hybrida: A Molecular Dynamics Study (2009) OPEN STRUCTURAL BIOLOGY JOURNAL, 3:84-93.

  • Karthikraja V, Suresh A, Lulu S, Kangueane U, Kangueane P., Types of interfaces for homodimer folding and binding (2009) BIOINFORMATION, 4:101-111.

  • Lulu S, Karthikraja V, Suresh A. Mohanapriya A, Kayathri R, Kangueane P, Structural features for homodimer folding mechanism (2009) J. Mol. Graphics. Modeling, 28: 88-94.

  • Mohanapriya A, Lulu S, Kayathri R, Kangueane P, Class II HLA-peptide binding prediction using structural principles, (2009) HUMAN IMMUNOLOGY, 70:159-169.

  • Kangueane P, Sakharkar M. Grouping of class I HLA alleles using electrostatic distribution maps of the peptide binding grooves. Methods in molecular biology (Clifton, N.J.) 409 , 175-81 (2007) PubMed ID:(18450000)

  • Kangueane P, Sakharkar M. HLA-peptide binding prediction using structural and modeling principles. Methods in molecular biology (Clifton, N.J.) 409 , 293-9 (2007) PubMed ID:(18450009)

  • Kangueane P, Sakharkar M. Structural basis for HLA-A2 supertypes. Methods in molecular biology (Clifton, N.J.) 409 , 155-62 (2007) PubMed ID:(18449998)    

  • Sakharkar M, Kangueane P, Sakharkar K, Zhong Z. Huge proteins in the human proteome and their participation in hereditary diseases. In silico biology 6 (4) , 275-9 (2006) PubMed ID:(16922691

  • Li L, Zhao B, Cui Z, Gan J, Sakharkar M, Kangueane P. Identification of hot spot residues at protein-protein interface. Bioinformation 1 (4) , 121-6 (2006) (Epub 04 Apr 2006) PubMed ID:(17597870

  • Shapshak P, Duncan R, Nath A, Turchan J, Pandjassarame K, Rodriguez H, Duran E, Ziegler F, Amaro E, Lewis A, Rodriguez A, Minagar A, Davis W, Seth R, Elkomy F, Chiappelli F, Kazic T. Gene chromosomal organization and expression in cultured human neurons exposed to cocaine and HIV-1 proteins gp120 and tat: drug abuse and NeuroAIDS. Frontiers in bioscience : a journal and virtual library 11 , 1774-93 (2006) (Epub 01 May 2006) PubMed ID:(16368555)  

  • Shapshak P, Duncan R, Turchan J, Nath A, Minagar A, Kangueane P, Davis W, Chiappelli F, Elkomy F, Seth R, Kazic T. Bioinformatics models in drug abuse and Neuro-AIDS: Using and developing databases. Bioinformation 1 (3) , 86-8 (2006) (Epub 22 Feb 2006) PubMed ID:(17597862)  

  • Yiting Y, Lei L, Sakharkar M, Kangueane P. Insight into gene fusion from molecular dynamics simulation of fused and un-fused IGPS (Imidazole Glycerol Phosphate Synthetase). Bioinformation 1 (3) , 99-104 (2006) (Epub 28 Feb 2006) PubMed ID:(17611615 )

  • Kangueane P. Welcome to "Bioinformation" a data journal. Bioinformation 1 (1) , 1 (2005) (Epub 01 Feb 2005) PubMed ID:(17597839 )

  • Kangueane P, Sakharkar M. T-Epitope Designer: A HLA-peptide binding prediction server. Bioinformation 1 (1) , 21-4 (2005) (Epub 15 May 2005) PubMed ID:(17597847)

  • Kangueane P, Sakharkar M, Rajaseger G, Bolisetty S, Sivasekari B, Zhao B, Ravichandran M, Shapshak P, Subbiah S. A framework to sub-type HLA supertypes. Frontiers in bioscience : a journal and virtual library 10 , 879-86 (2005) (Epub 01 Jan 2005) PubMed ID:(15569626 )  

  • Li L, Gan J, Cui Z, Sakharkar M, Kangueane P. Generation of a dataset for studying ligand effect on homodimer interface. Frontiers in bioscience : a journal and virtual library 10 , 1977-84 (2005) (Epub 01 May 2005) PubMed ID:(15769678 )  

  • Li L, Gunasekaran K, Gan J, Zhanhua C, Shapshak P, Sakharkar M, Kangueane P. Structural features differentiate the mechanisms between 2S (2 state) and 3S (3 state) folding homodimers. Bioinformation 1 (2) , 42-9 (2005) (Epub 02 Sep 2005) PubMed ID:(17597851 )  

  • Perumal B, Sakharkar K, Chow V, Pandjassarame K, Sakharkar M. Intron position conservation across eukaryotic lineages in tubulin genes. Frontiers in bioscience : a journal and virtual library 10 , 2412-9 (2005) (Epub 01 Sep 2005) PubMed ID:(15970504 )

  • Sakharkar K, Chaturvedi I, Chow V, Kwoh C, Kangueane P, Sakharkar M. u-Genome: a database on genome design in unicellular genomes. In silico biology 5 (5-6) , 611-5 (2005) PubMed ID:(16610139 )

  • Sakharkar M, Chow V, Ghosh K, Chaturvedi I, Lee P, Bagavathi S, Shapshak P, Subbiah S, Kangueane P. Computational prediction of SEG (single exon gene) function in humans. Frontiers in bioscience : a journal and virtual library 10 , 1382-95 (2005) (Epub 01 May 2005) PubMed ID:(15769633)  

  • Sakharkar M, Kangueane P, Perumal B, Chow V, Sorscher E, Sakharkar K, Hill A. Human genome -- from pieces to patterns. Frontiers in bioscience : a journal and virtual library 10 , 2576-84 (2005) (Epub 01 Sep 2005) PubMed ID:(15970519)  

  • Sakharkar M, Perumal B, Lim Y, Chern L, Yu Y, Kangueane P. Alternatively spliced human genes by exon skipping--a database (ASHESdb). In silico biology 5 (3) , 221-5 (2005) (Epub 08 Dec 2004) PubMed ID:(15984933)  

  • Sakharkar M, Perumal B, Sakharkar K, Kangueane P. An analysis on gene architecture in human and mouse genomes. In silico biology 5 (4) , 347-65 (2005) PubMed ID:(16268780 )  

  • Sakharkar M, Yiting Y, Chow V, Kangueane P. Insights to metabolic network evolution by fusion proteins. Frontiers in bioscience : a journal and virtual library 10 , 1070-8 (2005) (Epub 01 May 2005) PubMed ID:(15769606 )  

  • Zhanhua C, Gan J, Lei L, Mathura V, Sakharkar M, Kangueane P. Identification of critical heterodimer protein interface parameters by multi-dimensional scaling in euclidian space. Frontiers in bioscience : a journal and virtual library 10 , 844-52 (2005) (Epub 01 Jan 2005) PubMed ID:(15569623 )  

  • Zhanhua C, Gan J, Lei L, Sakharkar M, Kangueane P. Protein subunit interfaces: heterodimers versus homodimers. Bioinformation 1 (2) , 28-39 (2005) (Epub 11 Aug 2005) PubMed ID:(17597849)

  • Sakharkar M, Chow V, Chaturvedi I, Mathura V, Shapshak P, Kangueane P. A report on single exon genes (SEG) in eukaryotes. Frontiers in bioscience : a journal and virtual library 9 , 3262-7 (2004) (Epub 01 Sep 2004) PubMed ID:(15353355)  

  • Sakharkar M, Chow V, Kangueane P. Distributions of exons and introns in the human genome. In silico biology 4 (4) , 387-93 (2004) PubMed ID:(15217358)  

  • Sakharkar M, Kangueane P. Genome SEGE: a database for 'intronless' genes in eukaryotic genomes. BMC bioinformatics 5 , 67 (2004) (Epub 02 Jun 2004) PubMed ID:(15175116 )  

  • Yiting Y, Chaturvedi I, Meow L, Kangueane P, Sakharkar M. Can ends justify the means? Digging deep for human fusion genes of prokaryotic origin. Frontiers in bioscience : a journal and virtual library 9 , 2964-71 (2004) (Epub 01 Sep 2004) PubMed ID:(15353329)

  • Govindarajan K, Kangueane P, Tan T, Ranganathan S. MPID: MHC-Peptide Interaction Database for sequence-structure-function information on peptides binding to MHC molecules. Bioinformatics (Oxford, England) 19 (2) , 309-10 (2003) PubMed ID:(12538264 )

  • James J, Lakshmi B, Raviprasad V, Ananth M, Kangueane P, Gautam P. Insights from molecular dynamics simulations into pH-dependent enantioselective hydrolysis of ibuprofen esters by Candida rugosa lipase. Protein engineering 16 (12) , 1017-24 (2003) PubMed ID:(14983082 )  

  • Zhao B, Mathura V, Rajaseger G, Moochhala S, Sakharkar M, Kangueane P. A novel MHCp binding prediction model. Human immunology 64 (12) , 1123-43 (2003) PubMed ID:(14630395)

  • Sakharkar M, Kangueane P, Petrov D, Kolaskar A, Subbiah S. SEGE: A database on 'intron less/single exonic' genes from eukaryotes. Bioinformatics (Oxford, England) 18 (9) , 1266-7 (2002) PubMed ID:(12217920 )  

  • Kangueane P, Sakharkar M, Kolatkar P, Ren E. Towards the MHC-peptide combinatorics. Human immunology 62 (5) , 539-56 (2001) PubMed ID:(11334679

  • Kangueane P, Sakharkar M, Lim K, Hao H, Lin K, Chee R, Kolatkar P. Knowledge-based grouping of modeled HLA peptide complexes. Human immunology 61 (5) , 460-6 (2000) PubMed ID:(10773348)  

  • Ren E, Kangueane P, Kolatkar P, Lin M, Tseng L, Hansen J. Molecular modeling of the minor histocompatibility antigen HA-1 peptides binding to HLA-A alleles. Tissue antigens 55 (1) , 24-30 (2000) PubMed ID:(10703604 )  

  • Sakharkar M, Kangueane P, Woon T, Tan T, Kolatkar P, Long M, de Souza S. IE-Kb: intron exon knowledge base. Bioinformatics (Oxford, England) 16 (12) , 1151-2 (2000) PubMed ID:(11159334)  

  • Adrian P, Rajaseger G, Mathura V, Sakharkar M, Kangueane P. Types of inter-atomic interactions at the MHC-peptide interface: identifying commonality from accumulated data. BMC structural biology 2 , 2 (Epub 13 May 2002) PubMed ID:(12010576)  

  • Zhao B, Png A, Ren E, Kolatkar P, Mathura V, Sakharkar M, Kangueane P. Compression of functional space in HLA-A sequence diversity. Human immunology 64 (7) , 718-28 PubMed ID:(12826374)

  • Lakshmi BS, Kangueane P, Guo Y, Chen YZ, Gautam P. Molecular basis for the stereo-specificity of Candida rugosa lipase (CRL) towards ibuprofen. BIO-CATALYSIS AND BIOTRANSFORMATION. 17: 475 - 486, Jan 2000.

  • Lakshmi BS, Kangueane P, Madhavi K, Mukut K, Gautam P. Solvent hydrophobicity in the interfacial activation of Candida rugosa lipase. JOURNAL OF BIOCHEMISTRY, MOLECULAR BIOLOGY AND BIOPHYSICS. 4: 293-298, Feb 2000.

  • Lakshmi BS, Kangueane P, Abraham B, Pennathur G. Effect of vegetable oils in the secretion of lipase from Candida rugosa (DSM 2031). LETTERS IN APPLIED MICROBIOLOGY. 29: 66-70, Sep 1999.

    BOOKS (3)

  • Kangueane P., (Editor) Protein-protein Interactions, Hardcover, NOVA publisher, USA, 2010, ISBN: 978-1-61761-548-1, ~200 pages with 140 illus., approx. US $140.50

  • Kangueane P., (Single author) Bioinformation Discovery: From data to knowledge in Biology, SPRINGER. USA, 2009

  • Mathura V.S., Kangueane P., (ed). Bioinformatics: A Concept-Based Introduction, Pages 1-200, ISBN: 978-0-387-84869-3 e-ISBN: 978-0-387-84870-9, SPRINGER New York, USA, 2008

Books and book chapters (29)

  • Kangueane P, Sakharkar MK. Silico Biotech - Frontiers in Human Genetics: Diseases and Technologies. ISBN-10: 9810244584; ISBN-13: 978-9810244583, WORLD SCIENTIFIC Co. P. Ltd. Singapore (Chapter 5): pages 73-78, Jan 2001. Edited by L. P. San and E. P. H. Yap

  • Sakharkar M.K., Kangueane P., Long M., de Souza S. ExInt - An Exon Intron database. ENCYCLOPEDIA OF MEDICAL GENOMICS & PROTEOMICS (EMGP), ISBN: 978-0-8247-5502-7 (hardback) 978-0-8247-5501-0 (electronic), Marcel Dekker, Apr 2005. pages: 1-5, Edited by Jürgen Fuchs and Maurizio Podda

  • Kangueane P and Sakharkar MK. Structural basis for HLA-A2 super-types IMMUNO-INFORMATICS: PREDICTING IMMUNOGENICTY IN SILICO. Print ISBN: 978-1-58829-699-3, THE HUMANA PRESS INC. section 2, chapter 25, 2007, 155-162, Edited by Flower R. Darren

  • Kangueane P and Sakharkar MK. Grouping of HLA alleles using electrostatic distribution of the peptide binding groove. IMMUNO-INFORMATICS: PREDICTING IMMUNOGENICTY IN SILICO. Print ISBN: 978-1-58829-699-3, THE HUMANA PRESS INC. section 2, chapter 7, 2007, 175-181, Edited by Flower R. Darren

  • Kangueane P and Sakharkar MK. HLA-peptide binding prediction using structural and modeling principles. IMMUNO-INFORMATICS: PREDICTING IMMUNOGENICTY IN SILICO. Print ISBN: 978-1-58829-699-3, THE HUMANA PRESS INC. section 3, chapter 9, 2007, 293-300, Edited by Flower R. Darren

  • Kangueane P., R. Kayathri, M. Kishore Sakharkar, D. R. Flower, K. Sadler, F. Chiappelli, D. M. Segal, and P. Shapshak. Designing HIV gp120 peptide vaccines: rhetoric or reality for neuroAIDS, Chapter 9. In K. Goodkin, P. Shapshak, and A. Verma (ed.), The Spectrum of Neuro-AIDS Disorders: Pathophysiology, Diagnosis, and Treatment. ISBN: 9781555813697; ISBN10: 1555813690, ASM Press, Washington, DC, 105 – 119, (2008)

  • Shapshak, P., A. Minagar, P. Kangueane, S. Frost, S. L. Kosakovsky Pond, S. Zarate, E. Singer, D. Commins, A. De Groot, M. Quinones-Mateu, and E. Terwilliger. The role of viral genetic variability in HIV-1-associated neurocognitive disorders, Chapter 15. In K. Goodkin, P. Shapshak, and A. Verma (ed.), The Spectrum of Neuro-AIDS Disorders: Pathophysiology, Diagnosis, and Treatment. ISBN: 9781555813697; ISBN10: 1555813690, ASM Press, Washington, DC, 199-216 (2008)

  • M K Sakharkar, P. Kangueane, & V. Mathura, Biological Sequence Databases, Pages 39-46, Chapter 4, (In) Mathura V.S., Kangueane P. (ed.). Bioinformatics: A Concept-Based Introduction, ISBN: 978-0-387-84869-3 e-ISBN: 978-0-387-84870-9, SPRINGER New York, USA, 2008

  • A. Ramani, V. Mathura, C. Zhanhua, & P. Kangueane, Protein-Protein Interaction and Macromolecular Visualization, Pages 79-93, Chapter 7, (In) Mathura V.S., Kangueane P. (ed.). Bioinformatics: A Concept-Based Introduction, ISBN: 978-0-387-84869-3 e-ISBN: 978-0-387-84870-9, SPRINGER New York, USA, 2008

  • P. Kangueane, B. Zhao & M. K. Sakharkar, Computational Immunology: HLA-Peptide Binding Prediction, Pages 129-151, Chapter 11, (In) Mathura V.S., Kangueane P. (ed.). Bioinformatics: A Concept-Based Introduction, ISBN: 978-0-387-84869-3 e-ISBN: 978-0-387-84870-9, SPRINGER New York, USA, 2008

  • M. K. Sakharkar & P. Kangueane, Bioinformatics Application: Eukaryotic Gene Count and Evolution, Pages 155-162, Chapter 12, (In) Mathura V.S., Kangueane P. (ed.). Bioinformatics: A Concept-Based Introduction, ISBN: 978-0-387-84869-3 e-ISBN: 978-0-387-84870-9, SPRINGER New York, USA, 2008

  • M. K. Sakharkar, Y. Yu, & P. Kangueane, Bioinformatics Analysis: Gene Fusion, Pages 175-180, Chapter 14, (In) Mathura V.S., Kangueane P. (ed.). Bioinformatics: A Concept-Based Introduction, ISBN: 978-0-387-84869-3 e-ISBN: 978-0-387-84870-9, SPRINGER New York, USA, 2008

  • Kangueane P., Chapter 1: Introduction to Bioinformation Discovery, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 2: Creating datasets, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 3: Tools and Techniques, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 4: Protein subunits interactions, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 250 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 5: Homodimer folding and binding, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 6: Fusion proteins, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 7: MHC and peptide binding, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 8: HLA supertypes, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 9: T-epitope designer, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Kangueane P., Chapter 10: Eukaryotic genes, genomes, function, design and evolution, Bioinformation Discovery: From data to knowledge in Biology, Pages 1-250, ISBN: 978-1-4419-0518-5, Approx. 275 p. 82 illus., Hardcover, SPRINGER, New York, USA, 2009

  • Sowmya G, Vaishnavi A, Jigisha A, Kangueane P, (Editor: Kangueane P), Chapter 1: Protein-protein complexes, Book Title: Protein-protein Interactions, 978-1-61761-548-1, Hardcover, NOVA publisher, USA, 2010, approx. US $140.50

  • Tan JL, Sowmya G, Kangueane P, (Editor: Kangueane P) Chapter 3: Cancer fusion genes, Book Title: Protein-protein Interactions, 978-1-61761-548-1, Hardcover, NOVA publisher, USA, 2010, approx. US $140.50

  • Sowmya G, Vaishnavi A, Suresh A, Karthikraja V, Kangueane P, (Editor: Kangueane P) Chapter 9: Homodimer folding and binding, Book Title: Protein-protein Interactions, 978-1-61761-548-1, Hardcover, NOVA publisher, USA, 2010, approx. US $140.50

  • Li L, Vaishnavi A, Sowmya G, Kangueane P. (Editor: Kangueane P) Chapter 11, Interface hot spots in protein complexes, Book Title: Protein-protein Interactions, 978-1-61761-548-1, Hardcover, NOVA publisher, USA, 2010, approx. US $140.50

  • Shamini G, Ravichandran M, Kangueane P., (Editor: Kangueane P) Structural features of cholera toxin interface, Chapter 12: Book Title: Protein-protein Interactions, 978-1-61761-548-1, Hardcover, NOVA publisher, USA, 2010, approx. US $140.50

  • Nalayini S, Lalitha P., Kangueane P., (Editor: Kangueane P) Chapter 13: Taq DNA polymerase complexes, Book Title: Protein-protein Interactions, 978-1-61761-548-1, Hardcover, NOVA publisher, USA, 2010, approx. US $140.50

  • Yiting Y, Sakharkar MK, Kangueane P, (Editor: Kangueane P) Molecular dynamics in PPI (unfused) and fused homologous proteins, Book Title: Protein-protein Interactions, 978-1-61761-548-1, Hardcover, NOVA publisher, USA, 2010, approx. US $140.50

Conference presentations (50)

  • Kangueane P., Data, Database and Integration, National University of Singapore, Singapore, September 06, 2010 [Invited speaker and hosted by Tan Tin Wee]

  • Kangueane P., Bioinformation discovery for Bio-molecular design, Recent advances in Bioinformatics, KIIT University, Orissa, India, September 03, 2010 [Invited speaker]

  • Kangueane P., I, You, we, they, us – today, Anna University, Chennai Tamil Nadu, India, April 12, 2010 [Invited speaker]

  • Tan JL, Kangueane P., Cancer gene fusion, 21th Intervarsity Biochemistry Seminar, 27 March 2010, UCSI University, Kuala Lumpur, Malaysia [Oral Presentation]

  • Shamini G, Ravichandran M., Kangueane P., Protein-protein interactions in cholera toxin, 21th Intervarsity Biochemistry Seminar, 27 March 2010, UCSI University, Kuala Lumpur, Malaysia [Poster Presentation]

  • Kangueane P., I, You, we, they, us – today, TEDxVIT forum, VIT University, Vellore, Tamil Nadu, India, March 28, 2010 [Invited speaker]

  • Kangueane P., Peptide Vaccine Design, National Institute of Immunology, New Delhi, India, March 23, 2010 [Invited speaker] Hosted by Dr. Rajini Rani

  • Kangueane P., Naked Peptide Vaccine Designer Software, SBIRI, Department of Biotechnology, Ministry of Science and Technology, 23rd SBIRI technical screening committee meeting, venue at National Institute of Immunology, New Delhi, India, March 23, 2010 [Invited speaker] Hosted by Biotech Consortium Limited

  • Kangueane P, Bioinformation Discovery for Bio-molecular design, Bioinformatica Indica, Kerala University, India, January 11-13, 2010 [Invited Speaker]

  • Kangueane P, Bioinformation Discovery for Biotechnology, CRYSTAL, University of Malaya, Kuala Lumpur, Malaysia, December 17, 2009 [Invited Speaker]

  • Kangueane P, Biotechnology Investment, BioInvest 2009, ABLE India, Mumbai, Grand Hyatt, India, November 05, 2009 [Investment forum in Biotechnology]

  • Kangueane P, Designing short peptide vaccines, BITS World Anti-viral Workshop, Beijing International Convention Centre, Beijing, China, July 18- July 20, 2009 [Invited Speaker]

  • Kangueane P, PCR workshop, Bioinformatics Training for industry staff, OLIPRO Biotechnology, Klang, Kuala Lumpur, Malaysia, June 25- June 26, 2009 [Invited Speaker]

  • Kangueane P, Education and society, (Speech in Tamil language), AIMST University representative, 30th May, 2009, 2:30 PM, Sungai Petani, Shri Subramaniyar Temple, Kedha, Malaysia [Invited Speaker]

  • Kangueane P, Bioinformatics, human genetic data and novel discoveries, Department of Biotechnology, 19th Feb 2009, Jawaharlal Nehru Technological University, Kakinada, India. Host: Dr. Alam Appa Rao [Invited Speaker]

  • Kangueane P, Bioinformatics, human genetic data and novel discoveries, Department of Biotechnology, 17th Feb 2009, ANTHRA University, VIZAG, India. Host: Dr. Ramana [Invited Speaker]

  • Kangueane P, Bioinformatics, human genetic data and novel discoveries, Coalescence of Computer Science & Biotechnology" at Andhra University Platinum Jubilee Conference Hall-16th -17th Feb 2009 ANTHRA University, VIZAG, India. [Invited Speaker]

  • Kangueane P, Bioinformatics, human genetic data and discoveries, January 3 – January 5, 2009, Workshop on techniques in genomics in relation to diabetes and related disorders, MDRF, SIPCOT Siruseri, Chennai 603103, India. [Invited Speaker]

  • Kangueane P, Biotechnology investment, ABLE - BIOINVEST 2008, November 14-15, 2008, ITC Grand Maratha, Mumbai, India.

  • Kangueane P, Bioinformation Journal by Biomedical Informatics Publishing Group, Drug Discovery & Development of Innovative Therapeutics, India, October 20-28, 2008, Grand Hyatt Hotel, Mumbai, India. [Invited Press]

  • Kangueane P. Biomedical Informatics: 21st Century future in Health care, Universal Peace Federation, Pondicherry Chapter, India, October 03, 2008. Chaired by M. K. Rajan, Secretary, Universal Peace Federation [Invited Speaker]

  • Kangueane P. A story on SEG in eukaryotes, Seminar on Bioinformatics applications in Genomics, Pondicherry University, India, February 13-15, 2008. Chaired by P. P. Mathur & Vel Murugan [Invited Speaker]

  • Kangueane P. (2007) Science, Technology, Commerce and Economy, THE PUDUCHERRY INSTITUTE OF LINGUISTICS AND CULTURE, March 7, 2007. Chaired by Mr. N. Nandhivarman [Invited speaker]

  • Kangueane P. (2007) Insights from bioinformatics predictions, simulations & analysis. Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore, February 8, 2007. Chaired by Chen Yu Zong. [Invited speaker]

  • Kangueane P. (2007) Designing Peptide Vaccines: Rhetoric or Reality, International conference on biomarkers in health and environmental management, PSG College of Arts and College, Coimbatore, January 10 – January 12, 2007. [Invited speaker]

  • Kangueane P. Bioinformatics made Simple. – A one day course. C. Abdul Hakeem College, Melvisharam, Vellore District, Tamil Nadu, India, November 29, 2006. [Invited Speaker]

  • Kangueane P. Architectural evolution of human genes in genome design and putative function, Seminar on Bioinformatics and Functional Genomics, Pondicherry University, India, October 13, 2006. Chaired by P. P. Mathur [Invited Speaker]

  • Kangueane P. (2005) Designing Peptide Vaccines: Rhetoric or Reality, 5nd VIRTUAL CONFERENCE ON BIOINFORMATICS AND GENOMICS, Singapore Node, I2R, 25 October - 28 October 2005. [Invited speaker]

  • P Kangueane, Sub-typing HLA supertypes, Miami Miller Medical School, Miami, USA, 1 July, 2005. Hosted by Paul Shapshak. [Invited speaker]

  • P Kangueane & MK Sakharkar, An untold story on Single Exon Genes in Eukaryotes, 2nd Moscow Conference on Computational Molecular Biology (MCCMB'05), Moscow, Russia, July 18-21, 2005

  • P Kangueane & MK Sakharkar, Sub-typing HLA supertypes, 2nd Moscow Conference on Computational Molecular Biology (MCCMB'05), Moscow, Russia, July 18-21, 2005

  • P Shapshak, K Goodkin, R Duncan, J Turchan, A Nath, A Minagar, S. Shapshak, P. Kangueane, W. Davis, R. Seth, T. Kazic. Bioinformatics technologies for gene expression in human neurons in culture and brain - A model for international cooperation in gene expression. NIDA meeting in June in Orlando, June 2005.

  • P Shapshak, K Goodkin, R Duncan, A Nath, J Turchan, W Davis, P Kangueane,  EM Duran, F Ziegler, A Minagar, R Seth, & T Kazic. Gene expression in human neurons in culture and brain. Use of differing micro-array and bioinformatics technologies. 11th SNIP CONFERENCE, CLEARWATER BEACH, FLORIDA, April 6-10, 2005.

  • Sakharkar MK., Yiting Y., Kangueane P. (2004) Can Ends Justify the Means: To Fuse or Note to Fuse, INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND ITS APPLICATIONS, Nova Southeastern University, Fort Lauderdale, Florida, USA, December 2004.

  • Kangueane P. (2004). Designing B-cell epitopes for diagnosis through molecular modeling and comparative analysis. Page 27. Identification of potential markers for diagnosis of infectious diseases NATIONAL DIAGNOSTIC CONFERENCE AND WORKSHOP, Renaissance Hotel Kota Bharu, University of Science, Malaysia, October 4-5, 2004.  [Invited speaker]

  • Kangueane P. (2004). Selection of donor-recipient pairs in bone marrow transplantation: Insights from modeling and predictions. Page 32. Identification of potential markers for diagnosis of infectious diseases NATIONAL DIAGNOSTIC CONFERENCE AND WORKSHOP, Renaissance Hotel Kota Bharu, University of Science, Malaysia, October 4-5, 2004. [Invited speaker]

  • Kangueane P., Sakharkar MK., (2004) MHC function: Beyond Structures. PACIFIC SYMPOSIUM ON BIO-COMPUTING, Fairmont Orchid on the Big Island of Hawaii, USA, January 6-10 2004.

  • Sakharkar MK., Kangueane P., (2004) Intronless genes in Eukaryotes. PACIFIC SYMPOSIUM ON BIO-COMPUTING, Fairmont Orchid on the Big Island of Hawaii, USA, January 6-10 2004.

  • Jia Y., Kwoh C.K., Sakharkar M.K., Kangueane P., (2003) Statistical Analysis of Symmetric Exon Sets in Eukaryotic Genes, GENOME INFORMATICS 14: 410-411.

  • Sakharkar MK., Kangueane P., (2003) Genome wide distribution of intronless genes in Eukaryotes. ISCB ROCKY-1 BIOINFORMATICS MEETING, ASPEN, Colorado, USA. December 5-7 2003.

  • Kangueane P., Sakharkar MK., (2003) A Novel MHCp Binding Prediction. ISCB ROCKY-1 BIOINFORMATICS MEETING, ASPEN, Colorado, USA. December 5-7 2003

  • Sakharkar MK., Kangueane P. (2002) Intronless genes in Eukaryotes. CODATA 2002, 18th INTERNATIONAL CONFERENCE, Montreal, Canada, 29 September - 3 October 2002. Book of Abstracts, FRONTIER’S OF SCIENTIFIC AND TECHNICAL DATA, Page 54.

  • Kangueane P., Sakharkar MK., Liew KM. (2002) Towards T-cell Epitope Design. CODATA 2002, 18th INTERNATIONAL CONFERENCE, Montreal, Canada, 29 September - 3 October 2002. Book of Abstracts, FRONTIER’S OF SCIENTIFIC AND TECHNICAL DATA, Page 54.

  • Kangueane P. (2002) From Sequence to Proteome, 2nd VIRTUAL CONFERENCE ON BIOINFORMATICS AND GENOMICS, North Dekota State University, Fargo, USA, 24 September - 26 September 2002. [Invited speaker]

  • Sakharkar MK, Kangueane P, de Souza S, Subbiah S (2001) “MIDB (Mismatched intron Database) from ExInt”, Bioinformatics, BEYOND GENOME, Bioinformatics session (CHI conference) San Francisco, United States, June 17-19, 2001.

  • Pushparaj PN, Arockiam J, Baskar C, Kangueane P. (2001) Potential role of chemical information technology in 21st century science. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 222: 93-CINF Part 1, AMER. CHEMICAL SOC., Washington, USA.

  • Ren EC, Kangueane P, Kolatkar PR (2000) Knowledge based modeling of HLA-peptide binding, 26th Annual ASHI Meeting Abstracts Volume 61:S58, (Supplement 2), ‘‘The American Society for Histo-compatibility and Immuno-genetics’’ HUMAN IMMUNOLOGY, United States, ISSN 0198 8859.

  • Kangueane P, Sakharkar MK, Lim KS, Lin K, Ren EC, Brusic V, Kolatkar PR (1999) Strategies for EBV Vaccine Design using Computational Tools, P.15, Poster presented at ‘‘THE INTERNATIONAL SYMPOSIUM ON HUMAN GENETICS AND GENE THERAPY’’, 5-6 February 1999, Singapore. Appeared in ‘‘NEWSLETTER OF THE SINGAPORE SOCIETY FOR MICROBIOLOGY AND BIOTECHNOLOGY’’, SSMB-24, Jan-Mar 1999. ISSN 0218 3900.