Title
Insights from molecular network analysis to docking of sterubin with potential targets
Authors
Sittarthan Viswanathan1,*, Kavimani Subramanian1, Vimalavathini Ramesh1 & A. Hannah Rachel Vasanthi2
Affiliation
1Department of Pharmacology, Mother Theresa Post Graduate & Research Institute of Health Sciences (Government of Puducherry Institution), Puducherry - 605006, India; 2Department of Biotechnology, Pondicherry University - 605014;
Sittarthan Viswanathan - E-mail: insiddhu@gmail.com
Kavimani Subramanian - E-mail: drskavimani@yahoo.co.in
Ramesh Vimalavathini - E-mail: vimalavathini@gmail.com
Hannah Rachel Vasanthi - E-mail: hrvasanthi@gmail.com
Article Type
Research Article
Date
Received December 1, 2023; Revised December 31, 2023; Accepted December 31, 2023, Published December 31, 2023
Abstract
The use of a flavonoid compound sterubin in drug discovery is gaining momentum. Hence, it is of interest to document the molecular network analysis to docking of sterubin with potential targets to glean insights. We identified 32 target genes and (or) gene products for sterubin using DAVID tools for GO, KEGG pathway enrichment analyses and the STRING database. Further, molecular docking analysis data of sterubin with these targets is documented for further consideration in broad-spectrum drug discovery.
Keywords
Sterubin, Eriodicyton californicum, network analysis, molecular docking, Alzheimer’s disease.
Citation
Vishwanathan et al. Bioinformation 19(12): 1184-1192 (2023)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
